{"id":"W2998110188","doi":"10.1002/pro.3819","title":"Molecular mechanisms of vancomycin resistance","year":2020,"lang":"en","type":"review","venue":"Protein Science","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":367,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Vancomycin; Resistance (ecology); Computational biology; Genetics; Microbiology; Chemistry; Biology; Bacteria; Staphylococcus aureus; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002956362,0.0005429506,0.0004340285,0.0007676281,0.0002456752,0.001810293,0.0006712123,0.001347966,0.0009254916],"category_scores_gemma":[0.0003606736,0.0002390134,0.000332858,0.0004026351,0.000945375,0.0007982167,0.0006329094,0.001098408,0.0005870141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001445637,"about_ca_system_score_gemma":0.0005996198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006188992,"about_ca_topic_score_gemma":0.0003297353,"domain_scores_codex":[0.9995778,0.00006620251,0.00003394022,0.00009130224,0.0001420724,0.00008872285],"domain_scores_gemma":[0.9998306,0.00002899716,0.00006033266,0.00001234519,0.00003450767,0.00003318655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003203778,0.0001888456,0.002191014,0.001599731,0.00008836974,0.001801568,0.0002468785,0.003201856,0.7191903,0.1248873,0.005659127,0.1406246],"study_design_scores_gemma":[0.0001593833,0.001364119,0.01446265,0.0006408349,0.0001747063,0.008847954,0.0004133104,0.00964316,0.4353054,0.07656592,0.4522314,0.000191198],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1933079,0.6862464,0.06135747,0.01362319,0.001486372,0.0002697711,0.0009192878,0.0009650224,0.04182449],"genre_scores_gemma":[0.7007442,0.2710585,0.01046113,0.002445614,0.0005920707,0.0002049161,0.0006086062,0.00006106521,0.01382395],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001810293,"threshold_uncertainty_score":0.01048887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01564034819123746,"score_gpt":0.28028572114963,"score_spread":0.2646453729583925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}