{"id":"W2998202993","doi":"10.1002/pro.3811","title":"Structure of the full‐length <i>Serratia marcescens</i> acetyltransferase AAC(3)‐Ia in complex with coenzyme A","year":2019,"lang":"en","type":"article","venue":"Protein Science","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University of Calgary","funders":"Argonne National Laboratory; National Institute of Allergy and Infectious Diseases; National Institutes of Health; McMaster University; U.S. Department of Health and Human Services","keywords":"Stereochemistry; Enzyme; Serratia marcescens; Chemistry; Aminocyclitol; Dimer; Transferase; Serratia; Acetyltransferases; Biochemistry; Crystallography; Biology; Bacteria; Aminoglycoside; Antibiotics; Escherichia coli; Acetylation; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001621794,0.000399998,0.0004185502,0.0002119165,0.0003302374,0.0004226569,0.0005899919,0.0004634055,0.001495972],"category_scores_gemma":[0.0003820362,0.000187276,0.0003207044,0.0003495814,0.0002461608,0.0002560941,0.0001403956,0.0008794232,0.0003164571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008674097,"about_ca_system_score_gemma":0.0006907965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009487801,"about_ca_topic_score_gemma":0.007653197,"domain_scores_codex":[0.9998944,0.00001169025,0.000003763724,0.00001956958,0.00004722107,0.00002328852],"domain_scores_gemma":[0.999764,0.0000361873,0.00006835558,0.00001035486,0.00004905227,0.00007188335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001210598,0.0004008298,0.008987376,0.0003312542,0.0001422599,0.001959989,0.0003768397,0.003326945,0.9732627,0.001016146,0.00188066,0.007104479],"study_design_scores_gemma":[0.0006171566,0.002883379,0.3155622,0.0001295674,0.0003870751,0.007675535,0.001152752,0.07632198,0.5520028,0.001186584,0.04186543,0.0002155265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957635,0.00131858,0.0008160525,0.0001642378,0.00004307654,0.00001080218,0.0004901763,0.00008505924,0.001308527],"genre_scores_gemma":[0.9896875,0.0009317361,0.002303596,0.00006023022,0.00002332209,0.00001001993,0.004413369,0.00003524231,0.002534923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009487801,"threshold_uncertainty_score":0.01886517,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006476887531704361,"score_gpt":0.2183451524757247,"score_spread":0.2118682649440203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}