{"id":"W2998202993","doi":"10.1002/pro.3811","title":"Structure of the full‐length <i>Serratia marcescens</i> acetyltransferase AAC(3)‐Ia in complex with coenzyme A","year":2019,"lang":"en","type":"article","venue":"Protein Science","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University of Calgary","funders":"Argonne National Laboratory; National Institute of Allergy and Infectious Diseases; National Institutes of Health; McMaster University; U.S. Department of Health and Human Services","keywords":"Stereochemistry; Enzyme; Serratia marcescens; Chemistry; Aminocyclitol; Dimer; Transferase; Serratia; Acetyltransferases; Biochemistry; Crystallography; Biology; Bacteria; Aminoglycoside; Antibiotics; Escherichia coli; Acetylation; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004474744,0.0001765406,0.0002268605,0.00009430639,0.0001698762,0.00008165324,0.0008666383,0.00005836693,0.0007565538],"category_scores_gemma":[0.00005344052,0.0001018148,0.00003445719,0.001121328,0.0007948323,0.0004342188,0.0001132092,0.0002086996,0.00002346932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005479817,"about_ca_system_score_gemma":0.0002532172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001971831,"about_ca_topic_score_gemma":0.0006879032,"domain_scores_codex":[0.9979476,0.00007080108,0.0002722237,0.0005014882,0.0007998873,0.0004079982],"domain_scores_gemma":[0.9990001,0.00002381563,0.0001354712,0.0006261831,0.000141778,0.00007261818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001006554,0.00001539147,0.003002966,0.00004780127,0.000001130781,9.265574e-7,0.0004167947,0.0001754736,0.994683,0.001370309,0.00007035684,0.0001152],"study_design_scores_gemma":[0.0005387295,0.0001861452,0.0251992,0.00008271739,0.000004955171,0.00001939007,0.0001264022,0.0003132809,0.9725094,0.0005862996,0.0002693307,0.0001640967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997229,0.00002897381,0.0003876415,0.00030604,0.000241566,0.0009492325,0.00003215332,0.00002924361,0.0007961892],"genre_scores_gemma":[0.9966184,9.194077e-7,0.00306116,0.000173541,0.0000329651,0.00001141487,0.00000164861,0.00001073981,0.00008916448],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02219623,"threshold_uncertainty_score":0.8283733,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006476887531704361,"score_gpt":0.2183451524757247,"score_spread":0.2118682649440203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}