{"id":"W2998235022","doi":"10.3390/v12010064","title":"A Chimeric Sudan Virus-Like Particle Vaccine Candidate Produced by a Recombinant Baculovirus System Induces Specific Immune Responses in Mice and Horses","year":2020,"lang":"en","type":"article","venue":"Viruses","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada","funders":"","keywords":"Virus-like particle; Virology; VP40; Immunogenicity; Ebola virus; Virus; Antibody; Immune system; Adjuvant; Neutralizing antibody; Biology; Immunization; Vaccination; Recombinant DNA; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001765954,0.0004230066,0.0002287774,0.0003068627,0.0001315801,0.0002877918,0.0002100665,0.0004285286,0.0008789535],"category_scores_gemma":[0.0001094448,0.0001395488,0.0002802516,0.0001307455,0.0001870221,0.0001836599,0.0001645593,0.0006202165,0.0003144626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002514588,"about_ca_system_score_gemma":0.000142276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002559371,"about_ca_topic_score_gemma":0.0002722371,"domain_scores_codex":[0.9999061,0.00001767991,0.000007227203,0.00002433735,0.00002051477,0.0000241576],"domain_scores_gemma":[0.9999512,0.000007258572,0.00001523896,0.000007176962,0.000006852056,0.00001226014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005964034,0.00002928279,0.0000974971,0.00002258189,0.000004953828,0.00002759616,0.000008501678,0.0000701107,0.9988014,0.0001042306,0.00002190201,0.0007522896],"study_design_scores_gemma":[0.00005287983,0.00139336,0.003099964,0.00001425541,0.00004131137,0.0002923854,0.00002720609,0.001902268,0.988607,0.0001219528,0.004442069,0.000005262972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908103,0.001167667,0.005690425,0.00009363194,0.00004366907,0.00009638879,0.0002360111,0.0001086978,0.00175313],"genre_scores_gemma":[0.9903447,0.0007186913,0.004880263,0.00006745922,0.00001854713,0.00007812528,0.0008319098,0.00001704374,0.003043287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008789535,"threshold_uncertainty_score":0.002940416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04148966576230379,"score_gpt":0.3026838000768289,"score_spread":0.2611941343145252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}