{"id":"W2998270560","doi":"10.4084/mjhid.2020.001","title":"MOLECULAR MECHANISMS OF INHIBITOR DEVELOPMENT IN HEMOPHILIA","year":2020,"lang":"en","type":"review","venue":"Mediterranean Journal of Hematology and Infectious Diseases","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Thrombosis and Atherosclerosis Research Institute; McMaster Children's Hospital","funders":"","keywords":"Medicine; Population; Pathophysiology; Antibody; Factor IX; Intervention (counseling); Complication; Intensive care medicine; Pediatrics; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003542941,0.0006057459,0.0009498468,0.001645235,0.0002313948,0.0009626999,0.0005847854,0.0008492699,0.003255725],"category_scores_gemma":[0.0005776503,0.0001971339,0.000516369,0.001222795,0.0003214859,0.0008262041,0.0004383075,0.001275077,0.00127814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005782419,"about_ca_system_score_gemma":0.0008775305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008916461,"about_ca_topic_score_gemma":0.001111071,"domain_scores_codex":[0.9998314,0.00002940909,0.0000247486,0.00002524048,0.00006911845,0.0000199856],"domain_scores_gemma":[0.9998018,0.00008573264,0.00003840591,0.000005127722,0.00005413292,0.00001488823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001302488,0.00008238259,0.0004326529,0.03268233,0.000202366,0.0004401822,0.0001068815,0.0004784658,0.003825575,0.005644963,0.03523285,0.9207411],"study_design_scores_gemma":[0.00002649478,0.0001675829,0.001736065,0.005906248,0.0002493726,0.003327195,0.00007210673,0.0001134496,0.001331456,0.002624659,0.9844214,0.00002393622],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001249672,0.999051,0.00005448695,0.0001532662,0.00009261792,0.000003210559,0.00001416908,0.000003396991,0.0005028691],"genre_scores_gemma":[0.0007923162,0.9985951,0.00007305778,0.00009632533,0.00008470092,0.000003702457,0.00002492512,5.348815e-7,0.0003293266],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003255725,"threshold_uncertainty_score":0.0108915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03154176958977398,"score_gpt":0.3218833164719969,"score_spread":0.2903415468822229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}