{"id":"W2998270560","doi":"10.4084/mjhid.2020.001","title":"MOLECULAR MECHANISMS OF INHIBITOR DEVELOPMENT IN HEMOPHILIA","year":2020,"lang":"en","type":"review","venue":"Mediterranean Journal of Hematology and Infectious Diseases","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Thrombosis and Atherosclerosis Research Institute; McMaster Children's Hospital","funders":"","keywords":"Medicine; Population; Pathophysiology; Antibody; Factor IX; Intervention (counseling); Complication; Intensive care medicine; Pediatrics; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002442658,0.0003484582,0.002820309,0.0007315651,0.00004085412,0.000008846455,0.0001217136,0.0002941536,0.00009109644],"category_scores_gemma":[0.000366214,0.0002344853,0.0004482859,0.0003161785,0.0001839008,0.00006189524,0.00007063401,0.0005860926,0.000009910858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000948544,"about_ca_system_score_gemma":0.0009926702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":8.959179e-7,"about_ca_topic_score_gemma":0.000001150456,"domain_scores_codex":[0.9976439,0.0002349222,0.00123654,0.000238139,0.0003838393,0.0002626335],"domain_scores_gemma":[0.9985175,0.0002042067,0.0005806555,0.0001472906,0.0001456771,0.0004046448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003536904,0.001986705,0.002534045,0.0707697,0.002242112,0.0220389,0.0005370753,4.709327e-7,0.00003635241,0.0009128072,0.0009966821,0.8975915],"study_design_scores_gemma":[0.01333294,0.006114297,0.0003475796,0.1131774,0.009059129,0.05995188,0.0002345274,0.00001894711,0.003213126,0.003896724,0.7893028,0.001350697],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006214737,0.9925701,0.00006770767,0.0001836227,0.0003193196,0.0005073851,0.00001218033,0.00001168578,0.0001132457],"genre_scores_gemma":[0.03984154,0.9596905,0.0001388882,0.00005652962,0.0001613672,0.00002226306,0.00003199038,0.00003893805,0.00001801271],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8962408,"threshold_uncertainty_score":0.9562034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03154176958977398,"score_gpt":0.3218833164719969,"score_spread":0.2903415468822229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}