{"id":"W2998588974","doi":"10.3390/cancers12010055","title":"Single Nucleotide Polymorphism rs6942067 Is a Risk Factor in Young and in Non-Smoking Patients with HPV Negative Head and Neck Squamous Cell Carcinoma","year":2019,"lang":"en","type":"article","venue":"Cancers","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Common Fund; Institute of Cancer Research; National Human Genome Research Institute; National Institute on Drug Abuse; National Institute of Neurological Disorders and Stroke; National Heart, Lung, and Blood Institute; National Institute of Mental Health; NIH Office of the Director; Fonds de Recherche du Québec - Santé; National Cancer Institute; National Institutes of Health; Broad Institute; U.S. Department of Veterans Affairs","keywords":"Head and neck squamous-cell carcinoma; Single-nucleotide polymorphism; Oncology; Internal medicine; Medicine; SNP; Genotype; Head and neck cancer; Adenocarcinoma; Cancer research; Cancer; Biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003512224,0.0001517395,0.0001484939,0.00007183754,0.00003034076,0.00001690344,0.00004679501,0.0001197587,0.00001549246],"category_scores_gemma":[0.000009227744,0.0001515167,0.00001992694,0.000120173,0.00005361526,0.00001413092,0.00004366439,0.0001098845,9.711071e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003639558,"about_ca_system_score_gemma":0.00009873294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002748123,"about_ca_topic_score_gemma":0.002771916,"domain_scores_codex":[0.9991584,0.00002762574,0.0001422467,0.0003387676,0.00009369643,0.0002392498],"domain_scores_gemma":[0.999629,0.00001039515,0.0001053774,0.0001588432,0.00003051788,0.00006584026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002412167,0.00001669472,0.9738871,0.00002291239,0.000008702427,7.315664e-7,0.001099192,0.0004680969,0.02185764,1.634297e-7,0.00003765968,0.002359917],"study_design_scores_gemma":[0.003236955,0.0003710871,0.945893,0.00003223174,0.00001078895,0.000001250837,0.0001644725,0.0004251413,0.04954631,0.000003498877,0.0001122908,0.0002029585],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981749,0.0008490871,0.00000844349,0.00001415605,0.0001449874,0.0003597123,0.00006705475,0.000003759015,0.0003778859],"genre_scores_gemma":[0.9996313,0.00005666281,0.00006379964,0.00005534079,0.00004914748,0.00001099355,0.00001898161,0.00002607012,0.00008767955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02799405,"threshold_uncertainty_score":0.6178672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004584474841074165,"score_gpt":0.1986179484286188,"score_spread":0.1940334735875446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}