{"id":"W2998593800","doi":"10.3324/haematol.2019.235291","title":"The long non-coding RNA <i>Cancer Susceptibility 15</i> (<i>CASC15</i>) is induced by isocitrate dehydrogenase (IDH) mutations and maintains an immature phenotype in adult acute myeloid leukemia","year":2020,"lang":"en","type":"letter","venue":"Haematologica","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"BC Cancer Agency; Universität Ulm; Helmholtz Zentrum München; School of Medicine, Stanford University; Ludwig-Maximilians-Universität München","keywords":"Isocitrate dehydrogenase; IDH1; Molecular biology; Long non-coding RNA; RNA; Cancer research; Chemistry; Biology; Gene; Mutation; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003830047,0.0001607446,0.0002056785,0.0004118995,0.0004792692,0.0004842498,0.0001823946,0.0005612286,0.003606323],"category_scores_gemma":[0.001683745,0.0001111781,0.00009163256,0.0004812443,0.0003667226,0.0001878621,0.0002217035,0.0008091303,0.002534059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004486997,"about_ca_system_score_gemma":0.0002840743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008362983,"about_ca_topic_score_gemma":0.001885834,"domain_scores_codex":[0.9995947,0.00005634915,0.00004335187,0.0001268054,0.0001218756,0.00005687593],"domain_scores_gemma":[0.99891,0.0004062575,0.000131095,0.0001717507,0.0002151169,0.0001657585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004340892,0.0002152153,0.1450467,0.0005270515,0.0001144099,0.02160753,0.0005484897,0.0009562803,0.1515155,0.006349884,0.4451672,0.2236108],"study_design_scores_gemma":[0.0002086125,0.0005025612,0.1582357,0.0001622236,0.0001179443,0.06102886,0.0004485942,0.004221777,0.08168631,0.00788707,0.6854308,0.00006943567],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"editorial","genre_scores_codex":[0.7386043,0.01029296,0.01106628,0.1381523,0.0115654,0.0002824132,0.02794503,0.001243521,0.06084773],"genre_scores_gemma":[0.911103,0.00454316,0.005232482,0.0402262,0.005842276,0.0001593959,0.01162268,0.000296058,0.02097479],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.003606323,"threshold_uncertainty_score":0.01206434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01262041539646823,"score_gpt":0.2663825028896349,"score_spread":0.2537620874931666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}