{"id":"W2998672381","doi":"10.3390/ijms21010318","title":"Differential Subcellular Distribution and Translocation of Seven 14-3-3 Isoforms in Response to EGF and During the Cell Cycle","year":2020,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Subcellular localization; Gene isoform; Cell biology; Centrosome; Biology; Cell fractionation; Protein subcellular localization prediction; Organelle; Cytoplasm; Mitochondrion; Nucleus; Mitosis; Cell; Cell cycle; Biochemistry; Gene; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002657215,0.00005790138,0.00007117845,0.00005642083,0.00004111664,0.00003976061,0.0002401224,0.00003055168,0.000005756136],"category_scores_gemma":[0.0001567879,0.00004302158,0.00003915272,0.00009150943,0.0001022388,0.00001814413,0.00006742129,0.00007315363,3.678446e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001335731,"about_ca_system_score_gemma":0.00004949547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000137529,"about_ca_topic_score_gemma":0.000007641456,"domain_scores_codex":[0.9992605,0.00007074967,0.0002242315,0.0001194517,0.0002514195,0.00007368056],"domain_scores_gemma":[0.999626,0.00001910701,0.0001284624,0.00004705876,0.0001278927,0.00005142099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004026704,0.00002346901,0.001345724,0.000004307451,0.00001478488,0.000007605389,0.0003535569,0.0007345924,0.9963791,0.0000289516,0.000007780326,0.0006974576],"study_design_scores_gemma":[0.0004911907,0.0003257868,0.0200125,0.00003053555,0.000006120241,0.00006096335,0.0002934127,0.000378538,0.977964,0.00009997039,0.0002778654,0.00005915555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840364,0.0003022377,0.01235553,0.003115842,0.00008798634,0.00007452758,0.00001258,9.661667e-7,0.00001395584],"genre_scores_gemma":[0.999471,0.00008582908,0.0002834765,0.00009559064,0.00004697374,0.000002289554,0.000003211812,0.000003205413,0.00000840893],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01866678,"threshold_uncertainty_score":0.1754369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006180655410830642,"score_gpt":0.2499104876509634,"score_spread":0.2437298322401327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}