{"id":"W2998930842","doi":"10.1261/rna.070318.119","title":"Hypoxia influences polysome distribution of human ribosomal protein S12 and alternative splicing of ribosomal protein mRNAs","year":2020,"lang":"en","type":"article","venue":"RNA","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Scheme for Promotion of Academic and Research Collaboration; Canadian Institutes of Health Research; Hospital for Sick Children; Université de Sherbrooke","keywords":"Biology; Polysome; Ribosomal protein; Ribosome; Ribosomal RNA; Alternative splicing; Eukaryotic Ribosome; RNA splicing; Cell biology; Protein biosynthesis; Protein isoform; Gene isoform; Molecular biology; Biochemistry; RNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006343054,0.0001031723,0.0001465421,0.00001667327,0.00005751976,0.00001051525,0.0001329841,0.00007026386,0.000009101293],"category_scores_gemma":[0.00004012629,0.00009574661,0.00004849506,0.00008637323,0.0001341768,0.00000854142,0.00007201701,0.00006213326,0.000001036523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009237267,"about_ca_system_score_gemma":0.00004000194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001622059,"about_ca_topic_score_gemma":0.000009117085,"domain_scores_codex":[0.9992503,0.00003642785,0.0002375534,0.0002299497,0.0001218477,0.0001239543],"domain_scores_gemma":[0.9994989,0.000002822981,0.0001937427,0.0001516348,0.00008974738,0.00006314304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005307509,0.00003057915,0.00170436,0.00005170609,0.00003375404,6.710164e-7,0.00009210855,0.00002185041,0.9957113,0.001341029,0.000020944,0.0009386042],"study_design_scores_gemma":[0.0003188405,0.0004066964,0.01556312,0.00004971442,0.00001290272,0.000001221275,0.00006674778,0.00007648602,0.9828122,0.000179714,0.0004075268,0.000104826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980224,0.000382525,0.0006329427,0.0002982042,0.00001162014,0.0003109252,0.0001200889,0.000005836243,0.0002154117],"genre_scores_gemma":[0.99945,0.00002513369,0.0001670204,0.00002748072,0.0001180121,0.0000383764,0.00008432945,0.000008917295,0.00008078591],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01385876,"threshold_uncertainty_score":0.3904434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01725401323498041,"score_gpt":0.2608534245750433,"score_spread":0.2435994113400629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}