{"id":"W2999004039","doi":"10.1016/s2352-3026(19)30220-0","title":"Addition of anti-thymocyte globulin to standard graft-versus-host disease prophylaxis versus standard treatment alone in patients with haematological malignancies undergoing transplantation from unrelated donors: final analysis of a randomised, open-label, multicentre, phase 3 trial","year":2020,"lang":"en","type":"article","venue":"The Lancet Haematology","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; McGill University; BC Children's Hospital; Université Laval; Child and Family Research Institute; Hôtel-Dieu de Québec; CancerCare Manitoba; Capital District Health Authority; Royal Victoria Hospital; Centre hospitalier universitaire de Québec; Vancouver General Hospital; Princess Margaret Cancer Centre; University of British Columbia; Public Health Ontario; Dalhousie University; University of Toronto; McMaster University; Hôpital Maisonneuve-Rosemont; Juravinski Hospital","funders":"Canadian Institutes of Health Research; University of British Columbia; McMaster University; Sanofi","keywords":"Medicine; Anti-thymocyte globulin; Cumulative incidence; Internal medicine; Transplantation; Graft-versus-host disease; Hazard ratio; Surgery; Clinical endpoint; Tacrolimus; Randomized controlled trial; Gastroenterology; Confidence interval","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003012718,0.0003229374,0.002470728,0.0002185629,0.00007039943,0.00002252211,0.0002444744,0.0001450967,0.0001481121],"category_scores_gemma":[0.0003703246,0.0002128696,0.0001385977,0.001014421,0.0001863059,0.000121483,0.00003125216,0.0001576478,0.000006704431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001483564,"about_ca_system_score_gemma":0.0002934278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001844364,"about_ca_topic_score_gemma":0.0007589415,"domain_scores_codex":[0.9970556,0.0005551901,0.0009838423,0.0005155996,0.0005272683,0.0003625321],"domain_scores_gemma":[0.9973028,0.001425412,0.0004569682,0.000381358,0.000209562,0.0002238588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9727788,0.001197751,0.01898806,0.0004590094,0.001811363,0.0005139689,0.002795489,0.0006086414,0.0004217086,0.0001563694,0.0000225892,0.0002462564],"study_design_scores_gemma":[0.9485146,0.01689993,0.016967,0.0006371696,0.008244813,0.000006017849,0.0004611666,0.001091172,0.00685784,0.00002210924,0.00001806235,0.0002801053],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885255,0.0001336959,0.003021775,0.001039591,0.0001252068,0.004099295,0.002972066,0.00004205123,0.00004085332],"genre_scores_gemma":[0.9954768,0.0003275528,0.001982997,0.00008050996,0.00003091565,0.0001765896,0.001900091,0.00002290239,0.000001687743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02426418,"threshold_uncertainty_score":0.8680572,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07633850075544721,"score_gpt":0.3329399635474426,"score_spread":0.2566014627919954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}