{"id":"W2999024712","doi":"10.29173/hsi225","title":"Disease ‘interactome’ maps that may one day point to NEW diagnostics","year":2017,"lang":"en","type":"article","venue":"Health Science Inquiry","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Interactome; Disease; Computational biology; Point (geometry); Computer science; Bioinformatics; Biology; Medicine; Pathology; Genetics; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004552435,0.0001503457,0.0001488184,0.00008075305,0.0007756393,0.0002702538,0.0009312229,0.00004144788,0.00002874639],"category_scores_gemma":[0.0006588987,0.0001391561,0.00006720148,0.00007473463,0.000441713,0.00002161113,0.0005940195,0.00007247772,0.0000903301],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005315191,"about_ca_system_score_gemma":0.001472094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001850674,"about_ca_topic_score_gemma":0.00004153612,"domain_scores_codex":[0.9983352,0.00001854916,0.0001979115,0.0005802646,0.0002985989,0.0005694095],"domain_scores_gemma":[0.997149,0.00001360613,0.0001638977,0.001133598,0.00008750751,0.001452401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.0005946593,0.001163472,0.3421027,0.000360112,0.00006421012,0.000209799,0.003173623,0.0002626312,0.04894249,0.003231664,0.4564862,0.1434084],"study_design_scores_gemma":[0.0005391727,0.0004611179,0.8176976,0.0001692681,0.00001514292,0.00001337936,0.0002736238,0.00002596928,0.01056429,0.0008143061,0.1689169,0.0005092553],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798589,0.001256735,0.001561356,0.01411533,0.002101939,0.0004684631,0.00009102996,0.00001866495,0.0005276146],"genre_scores_gemma":[0.9910845,0.0007288035,0.0009610766,0.005787396,0.0007203122,0.00001582325,0.00004768846,0.00001658453,0.0006378526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4755949,"threshold_uncertainty_score":0.5965669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08257045948483406,"score_gpt":0.3808927823288678,"score_spread":0.2983223228440338,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}