{"id":"W2999024712","doi":"10.29173/hsi225","title":"Disease ‘interactome’ maps that may one day point to NEW diagnostics","year":2017,"lang":"en","type":"article","venue":"Health Science Inquiry","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Interactome; Disease; Computational biology; Point (geometry); Computer science; Bioinformatics; Biology; Medicine; Pathology; Genetics; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003702189,0.001189554,0.00129891,0.003427584,0.001169884,0.004117665,0.002269868,0.003994525,0.02122376],"category_scores_gemma":[0.01078359,0.0005931921,0.001216261,0.001789947,0.004236226,0.01248497,0.003606885,0.00534186,0.003399488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00108522,"about_ca_system_score_gemma":0.001465596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001285254,"about_ca_topic_score_gemma":0.001150387,"domain_scores_codex":[0.9991452,0.0002990053,0.00006485786,0.0001698303,0.0002111578,0.0001098972],"domain_scores_gemma":[0.987577,0.005953306,0.0009312204,0.002293883,0.001707189,0.001537456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0009881945,0.0002433649,0.01275902,0.001660843,0.0006475054,0.004697354,0.001577973,0.002928769,0.03426868,0.6363089,0.1381877,0.1657317],"study_design_scores_gemma":[0.00005238238,0.0001244531,0.009161577,0.0002311927,0.0001828246,0.002608813,0.001080051,0.001801722,0.00417408,0.6365062,0.3439647,0.0001120811],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.08342986,0.07303544,0.3702481,0.3243803,0.02202441,0.0002777381,0.01025317,0.005708761,0.1106423],"genre_scores_gemma":[0.5464323,0.05300188,0.2488554,0.07810494,0.02612036,0.0003546629,0.006618766,0.0009265065,0.03958524],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02122376,"threshold_uncertainty_score":0.07100052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08257045948483406,"score_gpt":0.3808927823288678,"score_spread":0.2983223228440338,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}