{"id":"W2999081633","doi":"10.1002/jcb.29595","title":"FOXC1 negatively regulates BMP‐SMAD activity and Id1 expression during osteoblast differentiation","year":2020,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"SMAD; Osteoblast; Bone morphogenetic protein; Transcription factor; Cell biology; Psychological repression; Bone morphogenetic protein 4; Signal transduction; BMPR2; Bone morphogenetic protein 2; Regulation of gene expression; Biology; Gene expression; Bone morphogenetic protein 7; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009002064,0.0001955077,0.0002115155,0.00002685022,0.00009649808,0.00005014753,0.0001935433,0.0001746964,0.00002144386],"category_scores_gemma":[0.0002100622,0.0001789119,0.0001338289,0.00006152859,0.00007898103,0.00001450926,0.0001503339,0.0001778352,0.000001381074],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001873508,"about_ca_system_score_gemma":0.00007611424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":7.697894e-7,"about_ca_topic_score_gemma":1.695403e-7,"domain_scores_codex":[0.9989446,0.00005338866,0.0003130353,0.0002743393,0.0002396121,0.0001750096],"domain_scores_gemma":[0.9989924,0.00001516807,0.0004432382,0.0001738377,0.0001361415,0.0002391728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004320246,0.00006822482,0.001279999,0.000185297,0.00006297231,0.00001507523,0.00009008674,0.00002852088,0.9973092,2.924999e-7,0.0001566196,0.0003717011],"study_design_scores_gemma":[0.0008371699,0.0001413513,0.003661878,0.0001087176,0.00004384656,0.00003072842,0.00008020858,0.00005624363,0.9947168,0.00001284177,0.0001214509,0.0001888156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963834,0.00172234,0.001566439,0.000135534,0.00005570675,0.00006828531,0.000009215258,0.00000982637,0.00004927586],"genre_scores_gemma":[0.9986342,0.00004437563,0.0005377643,0.00003409799,0.0005790259,0.000002242893,0.00002737882,0.00002545266,0.0001154477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002592439,"threshold_uncertainty_score":0.7295817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006800120289750505,"score_gpt":0.2063691246215092,"score_spread":0.1995690043317587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}