{"id":"W2999081633","doi":"10.1002/jcb.29595","title":"FOXC1 negatively regulates BMP‐SMAD activity and Id1 expression during osteoblast differentiation","year":2020,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"SMAD; Osteoblast; Bone morphogenetic protein; Transcription factor; Cell biology; Psychological repression; Bone morphogenetic protein 4; Signal transduction; BMPR2; Bone morphogenetic protein 2; Regulation of gene expression; Biology; Gene expression; Bone morphogenetic protein 7; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001684289,0.0002740285,0.0002343279,0.0003543767,0.0003137591,0.0003651833,0.000235093,0.0002873103,0.001322816],"category_scores_gemma":[0.0001513555,0.000182464,0.0001969195,0.0001518941,0.0003298595,0.0001326054,0.0002411698,0.000439226,0.0003904004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008755298,"about_ca_system_score_gemma":0.0007278593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00284656,"about_ca_topic_score_gemma":0.004713821,"domain_scores_codex":[0.9997743,0.00001619226,0.00001187768,0.00003465839,0.0000918571,0.00007113014],"domain_scores_gemma":[0.9998897,0.00001758858,0.00002359365,0.00000818082,0.00002330456,0.00003758307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007314212,0.00001155797,0.0008804981,0.00002651866,0.000002969403,0.00005679092,0.00001350999,0.0000405081,0.9975621,0.0002207475,0.00005350707,0.001058124],"study_design_scores_gemma":[0.00001115816,0.00004263673,0.0204869,0.000008195484,0.0000132732,0.0002066462,0.00002836959,0.0007302241,0.97463,0.00007536652,0.003762645,0.000004722123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880433,0.003913979,0.002946956,0.0001743116,0.00004710218,0.00002503253,0.0004064451,0.00005599896,0.004386816],"genre_scores_gemma":[0.9885434,0.001358776,0.001503885,0.000100911,0.00001443459,0.00003384753,0.0005517533,0.00002291305,0.007870219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00284656,"threshold_uncertainty_score":0.006352484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006800120289750505,"score_gpt":0.2063691246215092,"score_spread":0.1995690043317587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}