{"id":"W2999224494","doi":"10.1007/s40199-020-00326-z","title":"STAT3 inhibitory stattic enhances immunogenic cell death induced by chemotherapy in cancer cells","year":2020,"lang":"en","type":"article","venue":"DARU Journal of Pharmaceutical Sciences","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Immunogenic cell death; Doxorubicin; Apoptosis; MTT assay; Flow cytometry; Cancer cell; Secretion; Cancer research; Immune system; Immunotherapy; Chemistry; Biology; Medicine; Pharmacology; Cancer; Immunology; Chemotherapy; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004852111,0.0001384982,0.0003090335,0.0001109512,0.00008854066,0.00005207696,0.00022465,0.00004548221,0.001307432],"category_scores_gemma":[0.00004578921,0.00009997628,0.0001213731,0.0004630722,0.0001588739,0.0002678505,0.00002647621,0.0005685433,0.00001392626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001038016,"about_ca_system_score_gemma":0.0004317063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005566634,"about_ca_topic_score_gemma":0.000002082173,"domain_scores_codex":[0.9983472,0.00007388454,0.0005229971,0.0002011436,0.0005460238,0.000308769],"domain_scores_gemma":[0.9991503,0.000119966,0.0002228238,0.00005318596,0.0001100758,0.0003436511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002423854,0.0002453463,0.001035732,0.00003352834,0.00002552828,0.00002627902,0.0006052842,0.00003983051,0.9911314,0.00000755048,0.002518292,0.004088822],"study_design_scores_gemma":[0.001691143,0.001032841,0.0005930885,0.0001168268,0.0000484306,0.00002045715,0.0004395781,0.001031687,0.9745708,0.00002180443,0.02031809,0.0001152979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898373,0.002835212,0.0001451581,0.005929216,0.0004343989,0.0001300038,0.00001742792,0.00001000561,0.0006612884],"genre_scores_gemma":[0.994328,0.00153157,0.0003782519,0.003428744,0.0002952408,0.000002769138,9.324747e-7,0.000009916161,0.00002457545],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01779979,"threshold_uncertainty_score":0.9996055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09958713363301562,"score_gpt":0.4040039247936678,"score_spread":0.3044167911606522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}