{"id":"W2999376644","doi":"10.1172/jci130363","title":"The glucocorticoid receptor–FKBP51 complex contributes to fear conditioning and posttraumatic stress disorder","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; Canadian Institutes of Health Research; Centre for Addiction and Mental Health","keywords":"Glucocorticoid receptor; Posttraumatic stress; Anxiety; Major depressive disorder; Anxiety disorder; Psychology; Glucocorticoid; Fear conditioning; Internal medicine; Clinical psychology; Medicine; Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001050513,0.000266211,0.0001742915,0.0001668601,0.0001767135,0.0001788036,0.0001190685,0.0002303272,0.001302832],"category_scores_gemma":[0.0001708128,0.0001085566,0.0001467701,0.0001008117,0.0003083951,0.00008287975,0.0002012249,0.000416787,0.0001514941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002608757,"about_ca_system_score_gemma":0.0002007077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001088751,"about_ca_topic_score_gemma":0.0008541328,"domain_scores_codex":[0.9999146,0.00002175054,0.000005059316,0.00001373938,0.00002051545,0.00002440668],"domain_scores_gemma":[0.9999149,0.000008720874,0.00003360938,0.00000963841,0.000007482,0.00002561934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002777284,0.0003373975,0.01541753,0.0002228664,0.0001155498,0.001103883,0.0001079837,0.0003676465,0.9362641,0.001419147,0.001120681,0.04074596],"study_design_scores_gemma":[0.0002137967,0.001741189,0.7915324,0.00008057678,0.0003168198,0.004715299,0.0002239468,0.002381222,0.181872,0.002303931,0.01457965,0.00003919191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890537,0.005920991,0.001830801,0.0007156117,0.00007773245,0.00003091641,0.0001180133,0.00004964412,0.002202612],"genre_scores_gemma":[0.9965598,0.00188168,0.0003682642,0.0001142444,0.0000328737,0.000009878584,0.00007645188,0.000004177757,0.0009526302],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001302832,"threshold_uncertainty_score":0.004358411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1309324003268046,"score_gpt":0.3868164598756569,"score_spread":0.2558840595488523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}