{"id":"W2999383767","doi":"10.1038/s41416-019-0717-x","title":"Monocarboxylate transporter 1 blockade with AZD3965 inhibits lipid biosynthesis and increases tumour immune cell infiltration","year":2020,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":134,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"Cancer Research UK","keywords":"Immune system; Cancer research; Phosphocholine; Biology; Tumor microenvironment; Pharmacology; Chemistry; Biochemistry; Immunology; Phospholipid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009749427,0.0001337136,0.0002577055,0.00002977176,0.00005472254,0.00005464999,0.0001002111,0.00008442517,0.00004150181],"category_scores_gemma":[0.00002340702,0.0001337925,0.00009431448,0.0000816465,0.00006459033,0.00001899463,0.00001616174,0.0001460413,4.870876e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008127714,"about_ca_system_score_gemma":0.0001773619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002908285,"about_ca_topic_score_gemma":0.0004220292,"domain_scores_codex":[0.9991257,0.00003755947,0.0003204324,0.00018593,0.0001626536,0.0001676999],"domain_scores_gemma":[0.9993661,0.000006705484,0.0002377326,0.0000669798,0.0001431302,0.0001793262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004502586,0.00004594578,0.001528006,0.00004784081,0.00009910337,0.00002518744,0.00009550156,0.00008734249,0.9550756,6.549212e-7,0.0007960717,0.04174845],"study_design_scores_gemma":[0.001898897,0.0003731433,0.02637087,0.0001926449,0.0002046634,0.0005781409,0.00008645931,0.00001271076,0.8708245,0.000004514161,0.09920249,0.000251029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9283747,0.07064557,0.0001676026,0.0003759758,0.0001643368,0.0000885504,0.00005679407,0.000004879914,0.0001215876],"genre_scores_gemma":[0.9558293,0.04111796,0.0003033227,0.0004905846,0.002159351,0.000006374827,0.000009440911,0.00002529238,0.00005843369],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09840642,"threshold_uncertainty_score":0.54559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005879646172561709,"score_gpt":0.2012932345531769,"score_spread":0.1954135883806151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}