{"id":"W2999410272","doi":"10.1007/s00005-019-00566-1","title":"HER2-Positive Breast Cancer Immunotherapy: A Focus on Vaccine Development","year":2020,"lang":"en","type":"review","venue":"Archivum Immunologiae et Therapiae Experimentalis","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"Emmanuel Bible College; University of Waterloo","funders":"","keywords":"Trastuzumab; Pertuzumab; Immunotherapy; Medicine; Breast cancer; Monoclonal antibody; Immune system; Immunology; Immunogenicity; Antigen; Cancer vaccine; Cancer; Cancer immunotherapy; Clinical trial; Tumor microenvironment; Antibody; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007142713,0.0008330012,0.001210069,0.001688722,0.0002252337,0.0009177817,0.0008556299,0.001289369,0.002564388],"category_scores_gemma":[0.0005962129,0.0002827025,0.0004904449,0.001856021,0.0005116077,0.001603,0.0006217083,0.002563976,0.001592392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006204758,"about_ca_system_score_gemma":0.0009112665,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005840985,"about_ca_topic_score_gemma":0.0008728664,"domain_scores_codex":[0.9998272,0.00003158517,0.00001884404,0.00003435483,0.00006265535,0.00002529929],"domain_scores_gemma":[0.999705,0.0001397248,0.00003495879,0.00001023307,0.00007615797,0.00003393348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008344826,0.0001088705,0.0001218515,0.01210492,0.00005629289,0.0001475025,0.00004420802,0.0004491961,0.00301138,0.004982044,0.03019739,0.9486929],"study_design_scores_gemma":[0.00002335419,0.0001637309,0.0004876659,0.002779427,0.00006471605,0.0009811663,0.00004373131,0.0001175843,0.000729909,0.002072552,0.9925235,0.00001259651],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001019059,0.9988285,0.00009828797,0.0002771989,0.0002352415,0.000002786243,0.000007413298,0.000005021951,0.0004437194],"genre_scores_gemma":[0.0005028121,0.9986305,0.000124597,0.0002225238,0.0001620943,0.000004920862,0.00001597761,0.000001204793,0.0003354373],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002564388,"threshold_uncertainty_score":0.008578777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.024162047100398,"score_gpt":0.3206140666405289,"score_spread":0.296452019540131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}