{"id":"W2999444015","doi":"10.1002/hep.31115","title":"Indole Alleviates Diet‐Induced Hepatic Steatosis and Inflammation in a Manner Involving Myeloid Cell 6‐Phosphofructo‐2‐Kinase/Fructose‐2,6‐Biphosphatase 3","year":2020,"lang":"en","type":"article","venue":"Hepatology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canada Economic Development for Quebec Regions; U.S. Department of Veterans Affairs; National Institute on Alcohol Abuse and Alcoholism; National Institute of Food and Agriculture; National Institutes of Health; American Diabetes Association","keywords":"Steatosis; Inflammation; Indole test; Fatty liver; Proinflammatory cytokine; Internal medicine; Biology; Endocrinology; Fructose; Nonalcoholic fatty liver disease; Myeloid; Cancer research; Immunology; Medicine; Biochemistry; Disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001217643,0.0004240886,0.0004076007,0.0003523182,0.0001752675,0.0002100999,0.0001905212,0.0002540711,0.001171112],"category_scores_gemma":[0.00007045823,0.0001269953,0.0003718146,0.0001687116,0.0002819892,0.0001862084,0.0001664389,0.0006269353,0.0001762505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001977282,"about_ca_system_score_gemma":0.000380061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006970656,"about_ca_topic_score_gemma":0.001743396,"domain_scores_codex":[0.9999244,0.00001464592,0.000006147041,0.000009537591,0.00001645445,0.00002868472],"domain_scores_gemma":[0.999936,0.000004002792,0.00002625958,0.000005359899,0.000008783308,0.00001964123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003806558,0.0008221855,0.001068516,0.0002368239,0.00003738003,0.0001088291,0.00002795334,0.00009598957,0.9859832,0.0001091396,0.0001989257,0.007504527],"study_design_scores_gemma":[0.001418397,0.01540782,0.05990991,0.00009706687,0.0003164877,0.0007087332,0.0002074966,0.002672974,0.9094265,0.0003041878,0.009497321,0.0000331812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933859,0.002977116,0.001834898,0.0002264449,0.0000614198,0.00006474696,0.0002905601,0.0001338292,0.001025156],"genre_scores_gemma":[0.9934064,0.002544403,0.001586653,0.0001518889,0.00002950325,0.00006727231,0.0003377352,0.00001394286,0.001862259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001171112,"threshold_uncertainty_score":0.003917754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01342006655194449,"score_gpt":0.2287555386792725,"score_spread":0.215335472127328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}