{"id":"W2999553950","doi":"10.1038/s41467-019-14220-z","title":"Crystal structures of fukutin-related protein (FKRP), a ribitol-phosphate transferase related to muscular dystrophy","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Synchrotron Radiation Research Center; Connaught Fund; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; National Center of Neurology and Psychiatry; Japan Agency for Medical Research and Development; Takeda Science Foundation","keywords":"Transferase; Glycan; Chemistry; Biochemistry; Protein subunit; Glycosyltransferase; Biology; Glycoprotein; Enzyme; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003796067,0.0006569439,0.0006784892,0.0003093793,0.001256466,0.000840597,0.001281761,0.0008315262,0.002398496],"category_scores_gemma":[0.0008398031,0.0003934269,0.000306983,0.0007637808,0.0003565165,0.000626241,0.0004496856,0.002366181,0.0003600234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001650231,"about_ca_system_score_gemma":0.00107188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01043839,"about_ca_topic_score_gemma":0.01307778,"domain_scores_codex":[0.9996768,0.00004477154,0.00001358907,0.00005944295,0.0001441225,0.00006135333],"domain_scores_gemma":[0.9996352,0.00009918642,0.00005600496,0.00001816624,0.0001054028,0.00008598511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005172515,0.003362156,0.0325272,0.002534744,0.001121702,0.006498451,0.004029531,0.0320009,0.6518432,0.02153039,0.1551697,0.0842096],"study_design_scores_gemma":[0.003905014,0.002353081,0.1758321,0.0005055091,0.001185571,0.009846517,0.004858537,0.203385,0.3464168,0.008036101,0.2431592,0.0005164916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9648542,0.00938524,0.003941941,0.001853426,0.0003285811,0.00008243757,0.006187442,0.0005745706,0.01279201],"genre_scores_gemma":[0.9549677,0.00484883,0.01096481,0.0005779681,0.00006136514,0.0001487916,0.02230491,0.000209072,0.005916496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01043839,"threshold_uncertainty_score":0.02075523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008518573886820249,"score_gpt":0.2608757479683388,"score_spread":0.2523571740815185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}