{"id":"W2999687281","doi":"10.1016/j.jgo.2020.01.006","title":"Association of age with differences in immune related adverse events and survival of patients with advanced nonsmall cell lung cancer receiving pembrolizumab or nivolumab","year":2020,"lang":"en","type":"article","venue":"Journal of Geriatric Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Victoria; University of British Columbia","funders":"BC Cancer Agency","keywords":"Medicine; Pembrolizumab; Nivolumab; Internal medicine; Lung cancer; Cohort; Propensity score matching; Adverse effect; Odds ratio; Cancer; Cohort study; Retrospective cohort study; Oncology; Immunotherapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000378846,0.0002135415,0.0004032693,0.0003429189,0.0002353052,0.000537376,0.0002143493,0.0004918042,0.002057441],"category_scores_gemma":[0.001725649,0.0001655983,0.0006290217,0.0004704384,0.0001640454,0.0005302952,0.0002779973,0.0007370341,0.0002144487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002649793,"about_ca_system_score_gemma":0.0002283686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001530653,"about_ca_topic_score_gemma":0.001735946,"domain_scores_codex":[0.9996799,0.0000622115,0.00004155871,0.00008113716,0.000042905,0.00009230329],"domain_scores_gemma":[0.9985803,0.0003609488,0.0006149522,0.0000689757,0.00009013817,0.0002846785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001572425,0.00005215917,0.995924,0.000008170239,0.0001350871,0.00007772796,0.00002920815,0.0000879625,0.0005796392,0.0000226855,0.00006622897,0.001444666],"study_design_scores_gemma":[0.0000220963,0.0003273947,0.9988175,0.000002666095,0.0000614764,0.0001762184,0.00006742126,0.0002751568,0.00007081385,0.00003464623,0.0001404092,0.000004146799],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989115,0.000325295,0.00004596024,0.00004085528,0.00001461433,0.000002770694,0.0001857124,0.000002028715,0.0004712432],"genre_scores_gemma":[0.9995448,0.00007139922,0.00002231141,0.00002493132,0.00001906715,0.000002383415,0.0001594554,0.000001200583,0.0001544192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002057441,"threshold_uncertainty_score":0.006882787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008176792538313046,"score_gpt":0.2556021653125791,"score_spread":0.247425372774266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}