{"id":"W2999689547","doi":"10.1021/acs.biomac.0c00018","title":"Trehalose-Based Polyethers for Cryopreservation and Three-Dimensional Cell Scaffolds","year":2020,"lang":"en","type":"article","venue":"Biomacromolecules","topic":"Tardigrade Biology and Ecology","field":"Agricultural and Biological Sciences","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; University of Ottawa; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Cryoprotectant; Trehalose; Cryopreservation; Chemistry; Self-healing hydrogels; Viability assay; Biocompatibility; Cell; Tissue engineering; Biophysics; Cryobiology; Cell biology; Biochemistry; Biomedical engineering; Polymer chemistry; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006748696,0.0001093913,0.0001259227,0.000006542533,0.0001622978,0.00001922139,0.000113798,0.0001407585,0.00009892467],"category_scores_gemma":[0.00002769902,0.00004654756,0.00007106684,0.0001025132,0.00009161905,0.00003791724,0.00003581513,0.0000251853,0.00001429671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005786069,"about_ca_system_score_gemma":0.000008102817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005869625,"about_ca_topic_score_gemma":0.0003107086,"domain_scores_codex":[0.9993158,0.00003581707,0.0001176306,0.0002719605,0.00005846005,0.0002003199],"domain_scores_gemma":[0.9996235,0.0001694205,0.00005100495,0.00002712698,0.00002759748,0.0001014016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001534243,0.00004381832,0.0164459,0.00001283124,0.00001074311,0.000003628053,0.00001567861,0.000003304779,0.9749962,0.0001775467,0.001580957,0.006555934],"study_design_scores_gemma":[0.001609279,0.002806901,0.6904182,0.00001673192,0.00005819447,0.000008230504,0.00009194272,0.004457329,0.2539387,0.0016204,0.04434967,0.0006243173],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869962,0.000409971,0.00005212862,0.01204483,0.00005868441,0.0002119208,0.00008918703,0.0000611744,0.00007586834],"genre_scores_gemma":[0.9967536,0.000002766299,0.0007372237,0.002190237,0.0001339259,0.00002513294,0.0001381619,0.000001177205,0.00001779583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7210575,"threshold_uncertainty_score":0.1898154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02706312686703004,"score_gpt":0.2020347269145759,"score_spread":0.1749716000475458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}