{"id":"W2999689547","doi":"10.1021/acs.biomac.0c00018","title":"Trehalose-Based Polyethers for Cryopreservation and Three-Dimensional Cell Scaffolds","year":2020,"lang":"en","type":"article","venue":"Biomacromolecules","topic":"Tardigrade Biology and Ecology","field":"Agricultural and Biological Sciences","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; University of Ottawa; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Cryoprotectant; Trehalose; Cryopreservation; Chemistry; Self-healing hydrogels; Viability assay; Biocompatibility; Cell; Tissue engineering; Biophysics; Cryobiology; Cell biology; Biochemistry; Biomedical engineering; Polymer chemistry; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000188539,0.000386505,0.0001665929,0.0002842926,0.0001118707,0.000271182,0.0002409441,0.0003453992,0.00112888],"category_scores_gemma":[0.0002043938,0.0001384859,0.0002781755,0.0002343064,0.0001353747,0.0003816112,0.000231985,0.0004435096,0.0004296979],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002009218,"about_ca_system_score_gemma":0.0001611507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002655947,"about_ca_topic_score_gemma":0.0005980948,"domain_scores_codex":[0.9998633,0.0000145427,0.0000160335,0.00002588381,0.00005772036,0.00002251622],"domain_scores_gemma":[0.9998534,0.00003219488,0.00004672384,0.00001913392,0.00002779578,0.00002073895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001996905,0.00001181944,0.00004862836,0.00008026,0.000003742058,0.00008643336,0.00001713088,0.0003088262,0.9949332,0.0001741296,0.00003967134,0.004276143],"study_design_scores_gemma":[0.000003753304,0.0001236398,0.0006210612,0.000009032536,0.00000894126,0.0001757781,0.0000102204,0.0008647805,0.9944442,0.00006040035,0.003669629,0.000008635863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.900441,0.01020944,0.07907623,0.0001980208,0.0001736788,0.0002429744,0.001275622,0.0007082826,0.007674778],"genre_scores_gemma":[0.958838,0.004002949,0.03094442,0.00007341855,0.00002443252,0.0002182387,0.0007588891,0.00007721094,0.005062459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00112888,"threshold_uncertainty_score":0.003776491,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02706312686703004,"score_gpt":0.2020347269145759,"score_spread":0.1749716000475458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}