{"id":"W2999825619","doi":"10.1021/acscombsci.9b00202","title":"Antiproliferative Activities of Diimine-Based Mixed Ligand Copper(II) Complexes","year":2020,"lang":"en","type":"article","venue":"ACS Combinatorial Science","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"University of Isfahan; Fundação para a Ciência e a Tecnologia; Ministério da Ciência, Tecnologia e Ensino Superior; European Commission","keywords":"Chemistry; Diimine; Ligand (biochemistry); Reactive oxygen species; Stereochemistry; IC50; Viability assay; Intracellular; Apoptosis; In vitro; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001364113,0.0003648353,0.0002498328,0.0002191642,0.00008110364,0.0002313701,0.0003307434,0.0001977163,0.0004767799],"category_scores_gemma":[0.0001483086,0.000125979,0.00009358316,0.0002016476,0.0001261814,0.00009196714,0.0001803716,0.0002043681,0.0001322274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002800454,"about_ca_system_score_gemma":0.00008422753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002702773,"about_ca_topic_score_gemma":0.0005217228,"domain_scores_codex":[0.9998794,0.00003063649,0.00001403229,0.00002713911,0.00002576313,0.00002301299],"domain_scores_gemma":[0.9999262,0.00001145308,0.00002172875,0.000005605448,0.00001662984,0.00001834569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001880667,0.0000290694,0.0001143151,0.000152371,0.0000128722,0.00004201576,0.00002310033,0.0002243701,0.9968097,0.00006617475,0.0001010481,0.00223694],"study_design_scores_gemma":[0.000023313,0.0005694857,0.0007843275,0.00000904793,0.00002283746,0.0001184373,0.00001490759,0.0006090694,0.9959889,0.00001318672,0.001841043,0.000005535743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939272,0.003276522,0.001037868,0.00005172428,0.00002935614,0.00002184274,0.0001287005,0.00007701685,0.001449703],"genre_scores_gemma":[0.9952672,0.001221424,0.001751894,0.00003540391,0.00001345622,0.00002612932,0.0002272278,0.00001168449,0.001445668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004767799,"threshold_uncertainty_score":0.002031922,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05341484914410503,"score_gpt":0.2802279719992863,"score_spread":0.2268131228551813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}