{"id":"W2999911407","doi":"10.1002/jimd.12215","title":"Magnetic resonance imaging reveals specific anatomical changes in the brain of Agat‐ and Gamt‐mice attributed to creatine depletion and guanidinoacetate alteration","year":2020,"lang":"en","type":"article","venue":"Journal of Inherited Metabolic Disease","topic":"Muscle metabolism and nutrition","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; SickKids Foundation; Mental Health Research Canada; Toronto Centre for Phenogenomics; Hospital for Sick Children","funders":"","keywords":"Creatine; Magnetic resonance imaging; Nuclear magnetic resonance; Nuclear magnetic resonance spectroscopy; Medicine; Chemistry; Pathology; Internal medicine; Biology; Physics; Radiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002451011,0.0009482757,0.0004611517,0.001501977,0.0002375374,0.0003397359,0.0003606062,0.0006806318,0.003029807],"category_scores_gemma":[0.0003033211,0.0004286175,0.0003725267,0.0002793702,0.0008580961,0.0002740204,0.000427974,0.001107304,0.0005855988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002178088,"about_ca_system_score_gemma":0.0001459889,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000599583,"about_ca_topic_score_gemma":0.0009682287,"domain_scores_codex":[0.999716,0.00002838385,0.00003833072,0.0001028179,0.00006325467,0.00005108167],"domain_scores_gemma":[0.999455,0.00004040643,0.0002428253,0.0000322131,0.00003698939,0.000192598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002664153,0.00003576686,0.0003880448,0.00001553217,0.00001006912,0.0001336308,0.00002743957,0.00001830348,0.9986614,0.00004363847,0.00003348275,0.0003662441],"study_design_scores_gemma":[0.0001936922,0.002250441,0.1499089,0.00004944139,0.000172325,0.005849375,0.000388013,0.001885054,0.8359306,0.000401514,0.002918903,0.00005183771],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963666,0.000243582,0.001894544,0.0001019679,0.00002402136,0.00001706602,0.0007496485,0.0001241798,0.0004784803],"genre_scores_gemma":[0.9830784,0.0005235941,0.006068703,0.0001863213,0.00002339406,0.0001958223,0.001991753,0.0002612353,0.007670747],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003029807,"threshold_uncertainty_score":0.01013565,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01447243476441648,"score_gpt":0.2486292348254696,"score_spread":0.2341568000610531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}