{"id":"W3000024629","doi":"10.1016/j.clgc.2019.12.020","title":"A Randomized Phase II Trial of Prostate Boost Irradiation With Stereotactic Body Radiotherapy (SBRT) or Conventional Fractionation (CF) External Beam Radiotherapy (EBRT) in Locally Advanced Prostate Cancer: The PBS Trial (NCT03380806)","year":2020,"lang":"en","type":"article","venue":"Clinical Genitourinary Cancer","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; Impact; Ontario Clinical Oncology Group; McMaster University; Juravinski Cancer Centre","funders":"Sanofi","keywords":"Medicine; Brachytherapy; Prostate cancer; External beam radiotherapy; Dose fractionation; Radiation therapy; Randomized controlled trial; Prostate; Androgen deprivation therapy; Urology; Oncology; Nuclear medicine; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001803722,0.002836137,0.003003936,0.0005342186,0.0005068067,0.001142822,0.001406888,0.001761997,0.01998773],"category_scores_gemma":[0.001516125,0.0007993691,0.001752001,0.0006362161,0.001753829,0.001211736,0.0006674032,0.004713034,0.002714832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001001834,"about_ca_system_score_gemma":0.002116638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002002055,"about_ca_topic_score_gemma":0.004689052,"domain_scores_codex":[0.9994264,0.000313334,0.0000181443,0.0001308781,0.00003019268,0.00008114119],"domain_scores_gemma":[0.9993399,0.0001451855,0.0001179672,0.00006818961,0.00003401171,0.000294864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9724401,0.008360545,0.0003266408,0.000351379,0.0005117995,0.0000218926,0.00005748157,0.0004999487,0.002065623,0.0002559976,0.002236342,0.01287222],"study_design_scores_gemma":[0.9655061,0.03244199,0.0005612704,0.00001527183,0.0001482384,0.00001674735,0.00001651828,0.0002340346,0.0001532202,0.0002226551,0.0006755856,0.000008362753],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9659999,0.004028288,0.001752727,0.001956661,0.001650128,0.01006993,0.005008275,0.0004530182,0.009081108],"genre_scores_gemma":[0.944218,0.003849324,0.0049955,0.004044378,0.0009899603,0.01592739,0.007035728,0.0001658726,0.01877376],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01998773,"threshold_uncertainty_score":0.06686562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04768839545873921,"score_gpt":0.3980135810044481,"score_spread":0.3503251855457089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}