{"id":"W3000024629","doi":"10.1016/j.clgc.2019.12.020","title":"A Randomized Phase II Trial of Prostate Boost Irradiation With Stereotactic Body Radiotherapy (SBRT) or Conventional Fractionation (CF) External Beam Radiotherapy (EBRT) in Locally Advanced Prostate Cancer: The PBS Trial (NCT03380806)","year":2020,"lang":"en","type":"article","venue":"Clinical Genitourinary Cancer","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; Impact; Ontario Clinical Oncology Group; McMaster University; Juravinski Cancer Centre","funders":"Sanofi","keywords":"Medicine; Brachytherapy; Prostate cancer; External beam radiotherapy; Dose fractionation; Radiation therapy; Randomized controlled trial; Prostate; Androgen deprivation therapy; Urology; Oncology; Nuclear medicine; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001048497,0.0004815423,0.001661346,0.0001446496,0.0001936193,0.00005133854,0.0002144497,0.0001874778,0.0006755342],"category_scores_gemma":[0.000306416,0.0002923772,0.0005360178,0.0005862801,0.0004246504,0.0003718165,0.00004122995,0.0006453145,0.000003597319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007820676,"about_ca_system_score_gemma":0.002382444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002061044,"about_ca_topic_score_gemma":0.00004410992,"domain_scores_codex":[0.9952517,0.0006409856,0.001979181,0.0008370765,0.0008235897,0.0004674676],"domain_scores_gemma":[0.996407,0.00114884,0.00134759,0.000393465,0.0003622447,0.0003408656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9400437,0.005203616,0.004123285,0.000136145,0.001228225,0.0001478498,0.0008095854,0.001089436,0.0005058032,0.00001131522,0.001015531,0.04568546],"study_design_scores_gemma":[0.9423403,0.03677109,0.003512073,0.0004620017,0.000563773,0.0000191508,0.00007738007,0.004558854,0.0005641704,0.00003497123,0.01075717,0.0003391139],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9634347,0.009772897,0.0003711647,0.01215593,0.001415519,0.01254832,0.0001960891,0.00006546816,0.00003991069],"genre_scores_gemma":[0.9191794,0.06394057,0.0007406986,0.003566886,0.003288059,0.008162492,0.0001560557,0.0001132396,0.0008525956],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05416767,"threshold_uncertainty_score":0.9999529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04768839545873921,"score_gpt":0.3980135810044481,"score_spread":0.3503251855457089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}