{"id":"W3000094994","doi":"10.1634/theoncologist.2019-0777","title":"Exercise Intolerance in Anthracycline-Treated Breast Cancer Survivors: The Role of Skeletal Muscle Bioenergetics, Oxygenation, and Composition","year":2020,"lang":"en","type":"article","venue":"The Oncologist","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates; Susan G. Komen for the Cure","keywords":"Bioenergetics; Anthracycline; Skeletal muscle; Breast cancer; Exercise intolerance; Medicine; Internal medicine; Composition (language); Cancer; Oxygenation; Endocrinology; Biology; Heart failure; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001902923,0.00009237564,0.000220788,0.00002423956,0.00006984864,0.00001014965,0.0000822896,0.00006980627,0.0000257294],"category_scores_gemma":[0.00002221159,0.0000561772,0.00004678999,0.0002395791,0.0002911088,0.00004781195,0.00002606274,0.0001474842,0.000001822408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005772212,"about_ca_system_score_gemma":0.00004354131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002225089,"about_ca_topic_score_gemma":0.0006758462,"domain_scores_codex":[0.9993298,0.000076743,0.0002079,0.0001459686,0.0001329639,0.000106626],"domain_scores_gemma":[0.9995638,0.00006648524,0.0001024596,0.0001338417,0.00009023453,0.00004313875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003009161,0.0001660029,0.01217965,0.00005680554,0.00003797695,0.000004308989,0.002260355,0.0002718388,0.8989793,0.0001651092,0.0001073412,0.08547041],"study_design_scores_gemma":[0.00203002,0.0001980857,0.4538304,0.0002319148,0.0001168795,0.00002220524,0.001599539,0.006242686,0.5337072,0.0002670036,0.001606119,0.0001479493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791965,0.001168712,0.00003562144,0.01876825,0.00004036134,0.0003778041,0.00003285663,0.00002627705,0.0003535445],"genre_scores_gemma":[0.9975773,0.001428172,0.00004514244,0.0007316786,0.0001422347,0.00002819002,0.00002441712,0.000009749559,0.00001318755],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4416507,"threshold_uncertainty_score":0.3363684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01337186505007129,"score_gpt":0.2708306323130751,"score_spread":0.2574587672630038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}