{"id":"W3000187202","doi":"10.1016/j.neuron.2019.12.028","title":"LRRTM4: A Novel Regulator of Presynaptic Inhibition and Ribbon Synapse Arrangements of Retinal Bipolar Cells","year":2020,"lang":"en","type":"article","venue":"Neuron","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"National Eye Institute; Luonnontieteiden ja Tekniikan Tutkimuksen Toimikunta; Canadian Institutes of Health Research; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Research to Prevent Blindness","keywords":"Ribbon synapse; Neuroscience; GABAergic; Postsynaptic potential; Synapse; Glutamatergic; Cell biology; Biology; Axon; Glutamate receptor; Synaptic vesicle; Inhibitory postsynaptic potential; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001498728,0.000540569,0.0004144457,0.000352062,0.0004377467,0.0006457652,0.0008638605,0.0005661956,0.001870805],"category_scores_gemma":[0.0001757575,0.0002476956,0.0003724864,0.0002106405,0.0004024846,0.0003208013,0.0004082116,0.0005242909,0.0008916325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007190426,"about_ca_system_score_gemma":0.0002539183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006442067,"about_ca_topic_score_gemma":0.0007669851,"domain_scores_codex":[0.9998736,0.00001736799,0.000007294341,0.00004306316,0.00003472566,0.00002393516],"domain_scores_gemma":[0.9999185,0.00000814105,0.00002845248,0.00000911624,0.000008533717,0.00002718903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001999908,0.00001742816,0.0004780461,0.00004494682,0.00001384374,0.0005543465,0.00001467584,0.0002864061,0.995265,0.0005518123,0.0002820763,0.002291423],"study_design_scores_gemma":[0.00007275918,0.0001549875,0.01569834,0.00001270199,0.00006997635,0.00351598,0.00006732577,0.007819738,0.9628425,0.0005887115,0.009124627,0.00003235135],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9721061,0.003400714,0.01692495,0.0003866385,0.0001579666,0.00005076277,0.0009267858,0.000842526,0.005203598],"genre_scores_gemma":[0.9841186,0.000712117,0.007639977,0.0001289825,0.00003952206,0.000038123,0.001171976,0.000126649,0.006024083],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001870805,"threshold_uncertainty_score":0.006258488,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01030402725368979,"score_gpt":0.2028220402853319,"score_spread":0.1925180130316421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}