{"id":"W3000285473","doi":"10.1038/s10038-019-0720-3","title":"Genome-wide meta-analysis associates GPSM1 with type 2 diabetes, a plausible gene involved in skeletal muscle function","year":2020,"lang":"en","type":"review","venue":"Journal of Human Genetics","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Natural Science Foundation of China","keywords":"Expression quantitative trait loci; Biology; Single-nucleotide polymorphism; Skeletal muscle; Genome-wide association study; Epigenetics; Genetics; CTCF; Allele; Genetic association; Locus (genetics); Gene; Gene expression; Genotype; Endocrinology; Enhancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003022874,0.0004852712,0.002462505,0.0003266555,0.00007165282,0.00007843241,0.0004092995,0.0003241568,0.0001293806],"category_scores_gemma":[0.00008056363,0.0003484676,0.001998648,0.0005854955,0.0000680028,0.000006528384,0.0001330366,0.0004077318,0.000006636748],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007304436,"about_ca_system_score_gemma":0.0004274504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004172855,"about_ca_topic_score_gemma":0.0001298136,"domain_scores_codex":[0.9974885,0.0002641125,0.001059298,0.0004343871,0.0004094751,0.0003442426],"domain_scores_gemma":[0.9977573,0.00004262545,0.001316704,0.0003570875,0.0002734504,0.0002528591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002577357,0.002111117,0.02482094,0.01082228,0.8876482,0.001053773,0.0002343067,0.007329225,0.01118763,0.0000297179,0.003960842,0.05054422],"study_design_scores_gemma":[0.0006918653,0.00182908,0.001881017,0.0001631931,0.2932567,0.00001063002,0.00003399999,0.00001573392,0.0002488831,0.00003348921,0.7011369,0.0006984494],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03762434,0.9618534,0.00005671688,0.00001493492,0.0000704097,0.0002413585,0.00007446546,0.000004439758,0.00005993267],"genre_scores_gemma":[0.02604265,0.9722429,0.0005141087,0.000102721,0.0003651575,0.0000196708,0.0004999291,0.00007565072,0.0001372186],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6971761,"threshold_uncertainty_score":0.9998967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04057585698204191,"score_gpt":0.2897502470216412,"score_spread":0.2491743900395993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}