{"id":"W3000359011","doi":"10.1177/1087054719896853","title":"Efficacy and Safety of PRC-063, Extended-Release Multilayer Methylphenidate in Adults with ADHD Including 6-Month Open-Label Extension","year":2020,"lang":"en","type":"article","venue":"Journal of Attention Disorders","topic":"Attention Deficit Hyperactivity Disorder","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Purdue Pharma (Canada)","funders":"Purdue Pharma","keywords":"Methylphenidate; Placebo; Open label; Psychology; Double blind; Insomnia; Adverse effect; Population; Rating scale; Safety profile; Psychiatry; Medicine; Internal medicine; Attention deficit hyperactivity disorder","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009352071,0.000474957,0.001030743,0.0001679846,0.0002147749,0.0002736716,0.0005139112,0.000595566,0.002593379],"category_scores_gemma":[0.001232692,0.0002776948,0.0004963969,0.0002196302,0.0003344284,0.0004009909,0.0002313198,0.0008940524,0.000378731],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003206548,"about_ca_system_score_gemma":0.0005483373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000986035,"about_ca_topic_score_gemma":0.002330541,"domain_scores_codex":[0.9996438,0.0001360056,0.00005373186,0.00006034314,0.00007565132,0.00003041695],"domain_scores_gemma":[0.9993279,0.0001299894,0.0002889351,0.00006566237,0.00006233079,0.000125278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7414035,0.01932869,0.009631681,0.001439728,0.001020049,0.0001140722,0.0002325185,0.0006388813,0.04845028,0.00004995246,0.0006456089,0.1770451],"study_design_scores_gemma":[0.3197099,0.5833433,0.08368345,0.00009291799,0.0009944579,0.0004000469,0.00008567879,0.001301914,0.008994255,0.00005111223,0.001299919,0.00004287976],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975871,0.001255125,0.0001854385,0.00004453951,0.00002048301,0.0003538051,0.000236696,0.00003736234,0.0002794847],"genre_scores_gemma":[0.9970783,0.0008309907,0.0009941087,0.00008184746,0.00005436023,0.000277043,0.0003048537,0.000006561308,0.0003720836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002593379,"threshold_uncertainty_score":0.008675694,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06235247840871193,"score_gpt":0.3516334877378947,"score_spread":0.2892810093291827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}