{"id":"W3000477794","doi":"10.1093/cid/ciaa035","title":"Clinical Impact of Metagenomic Next-Generation Sequencing of Plasma Cell-Free DNA for the Diagnosis of Infectious Diseases: A Multicenter Retrospective Cohort Study","year":2020,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Blood groups and transfusion","field":"Medicine","cited_by":332,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Retrospective cohort study; Medicine; Cohort; Clinical Practice; Cohort study; Metagenomics; DNA sequencing; Internal medicine; Biology; DNA; Physical therapy; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08931037648120649,"score_gpt":0.3709220067322309,"score_spread":0.2816116302510244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."},"direct_labels":[],"classifier":{"requested":true,"available":true,"version":"metacan-v1-d91a1de5be90","frame_rows_covered":4299418,"decision_targets":["metaresearch","metaepi_narrow","metaepi_broad","bibliometrics","sts","scholarly_communication","open_science","research_integrity","randomized_trial","nonrandomized_trial","observational","systematic_review","meta_analysis","case_report","qualitative","simulation_or_modeling","bench_or_experimental","theoretical_or_conceptual","not_applicable"],"score_encoding":"uint16_le_65535","score_resolution":0.000015259021896696422,"interpretation":"Scores imitate each teacher on the enriched screening sample; they are not calibrated prevalence probabilities for the full frame.","warning":null},"prediction":{"classifier_version":"metacan-v1-d91a1de5be90","candidate_union":["observational"],"consensus_intersection":["observational"],"score_encoding":"uint16_le_65535","score_resolution":0.000015259021896696422,"scores":{"codex":{"metaresearch":0.002105745021744106,"metaepi_narrow":0.000030518043793392844,"metaepi_broad":0.0003509575036240177,"bibliometrics":0.00006103608758678569,"sts":0.0008850232700083925,"scholarly_communication":0.00006103608758678569,"open_science":0.00007629510948348211,"research_integrity":0.0005493247882810712,"randomized_trial":0.00024414435034714275,"nonrandomized_trial":0.00025940337224383917,"observational":0.9999237048905165,"systematic_review":0.00007629510948348211,"meta_analysis":0.0004882887006942855,"case_report":0.00006103608758678569,"qualitative":0.000030518043793392844,"simulation_or_modeling":0.0019378957808804456,"bench_or_experimental":0.0007324330510414282,"theoretical_or_conceptual":0.00039673456931410697,"not_applicable":0.00019836728465705348,"design_other":0.00015259021896696422},"gemma":{"metaresearch":0.0020904859998474097,"metaepi_narrow":0.00006103608758678569,"metaepi_broad":0.000030518043793392844,"bibliometrics":0.000030518043793392844,"sts":0.000015259021896696422,"scholarly_communication":0.000015259021896696422,"open_science":0.00009155413138017853,"research_integrity":0.0034180209048599985,"randomized_trial":0.0007629510948348211,"nonrandomized_trial":0.0002136263065537499,"observational":0.9920347905699245,"systematic_review":0.00009155413138017853,"meta_analysis":0.00038147554741741054,"case_report":0.00024414435034714275,"qualitative":0.00009155413138017853,"simulation_or_modeling":0.0053711757076371405,"bench_or_experimental":0.008850232700083924,"theoretical_or_conceptual":0.004837109941252766,"not_applicable":0.000015259021896696422}},"interpretation":"Scores imitate each teacher on the enriched screening sample; they are not calibrated prevalence probabilities for the full frame."}}