{"id":"W3000563621","doi":"10.1016/s0923-7534(20)33006-4","title":"A Phase I Study of the Combination of RO4929097 (RO) And Cediranib (CD) in Patients with Advanced Solid Tumors (PJC-004/NCI 8503)","year":2012,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Juravinski Cancer Centre","funders":"","keywords":"Medicine; Internal medicine; Solid tumor; Oncology; Pharmacology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001517832,0.001502082,0.002341738,0.0006594597,0.0005151,0.001170394,0.001218964,0.001398605,0.003453166],"category_scores_gemma":[0.0009431132,0.0007262996,0.001691627,0.000622305,0.001135053,0.0009303392,0.0004026105,0.003990849,0.001218516],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001146017,"about_ca_system_score_gemma":0.001834124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002411109,"about_ca_topic_score_gemma":0.006421342,"domain_scores_codex":[0.999519,0.0002235382,0.00002157204,0.00008823683,0.00003934265,0.0001083538],"domain_scores_gemma":[0.999226,0.0001258024,0.00008892995,0.00007809724,0.0000336371,0.0004475879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6420227,0.1035309,0.01009419,0.0008164106,0.002963094,0.0005358442,0.0005027942,0.005770353,0.06955032,0.0008371871,0.008134581,0.1552416],"study_design_scores_gemma":[0.5051411,0.470969,0.0126717,0.00003008555,0.0007102201,0.0004856691,0.00009531706,0.00155622,0.003495259,0.0002571269,0.004540875,0.0000475064],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893629,0.002796018,0.0007219446,0.0007739214,0.0002075521,0.001808211,0.00128399,0.0001524783,0.002892992],"genre_scores_gemma":[0.9854431,0.002615007,0.002812149,0.001054436,0.0002060034,0.001690005,0.002841055,0.00005800744,0.003280184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003453166,"threshold_uncertainty_score":0.01155198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02007739141885191,"score_gpt":0.331929987235126,"score_spread":0.3118525958162741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}