{"id":"W3000573797","doi":"10.1016/j.clinbiochem.2020.01.002","title":"P4 medicine or O4 medicine? The perils of population wide, asymptomatic disease screening","year":2020,"lang":"en","type":"letter","venue":"Clinical Biochemistry","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Asymptomatic; Disease; Medicine; Population; Intensive care medicine; Internal medicine; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003589109,0.0005222511,0.00149196,0.00005378783,0.00009980184,0.00001241454,0.0003821061,0.0005725991,0.001529414],"category_scores_gemma":[0.005674188,0.0002663439,0.0005721169,0.0002695184,0.0009446117,0.00002973762,0.000138824,0.001281394,0.00003179648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007575683,"about_ca_system_score_gemma":0.0002710261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009118374,"about_ca_topic_score_gemma":6.900975e-7,"domain_scores_codex":[0.995965,0.0001741927,0.001644855,0.0008460784,0.001029807,0.0003400614],"domain_scores_gemma":[0.9942368,0.002947581,0.0008003304,0.001216434,0.0002031866,0.0005956985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.0004718925,0.0002049602,0.0806856,0.002387928,0.0007940296,0.001215416,0.00004429458,2.447091e-7,0.00003177162,0.000002047014,0.9114493,0.002712501],"study_design_scores_gemma":[0.01754264,0.003428604,0.5501407,0.03209552,0.02899351,0.00009690221,0.0004487586,0.0006533092,0.0008265354,0.0006938131,0.363456,0.001623711],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.03469374,0.003439402,0.00002224479,0.9594849,0.0004369713,0.000872486,0.0001702529,0.00009989728,0.0007800586],"genre_scores_gemma":[0.3421361,0.0008451014,0.0001545684,0.6373191,0.01227091,0.0001175895,0.005679515,0.00008950733,0.001387657],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.5479932,"threshold_uncertainty_score":0.9999789,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08579226792601731,"score_gpt":0.383519142950306,"score_spread":0.2977268750242887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}