{"id":"W3000573797","doi":"10.1016/j.clinbiochem.2020.01.002","title":"P4 medicine or O4 medicine? The perils of population wide, asymptomatic disease screening","year":2020,"lang":"en","type":"letter","venue":"Clinical Biochemistry","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Asymptomatic; Disease; Medicine; Population; Intensive care medicine; Internal medicine; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007519761,0.0007783967,0.001357575,0.0009223185,0.007279099,0.006421233,0.001904637,0.08970121,0.01446304],"category_scores_gemma":[0.03270167,0.000851265,0.0009898933,0.000817109,0.00657922,0.00678862,0.003241128,0.05435267,0.006162707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005623587,"about_ca_system_score_gemma":0.01210593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01690061,"about_ca_topic_score_gemma":0.03500927,"domain_scores_codex":[0.9922996,0.003305733,0.0006157036,0.0007860331,0.001750342,0.001242609],"domain_scores_gemma":[0.9744456,0.01198014,0.001066853,0.0006847641,0.002782249,0.009040356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000814406,0.00008191365,0.001710198,0.00006771291,0.00001745144,0.002084868,0.0002357945,0.00006109907,0.0002288342,0.01165915,0.9727581,0.0110134],"study_design_scores_gemma":[0.0002140378,0.0001361917,0.003765296,0.0006878681,0.00002900699,0.002851358,0.001419726,0.0006436878,0.0001536776,0.03312342,0.9568653,0.0001105619],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0002268868,0.0004094667,0.00004397797,0.9916386,0.004614067,0.000006225855,0.00001906168,0.000007003029,0.003034823],"genre_scores_gemma":[0.002505563,0.0004447858,0.0002005137,0.973316,0.01675497,0.00002551236,0.00001398538,0.00001365062,0.006725016],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.08970121,"threshold_uncertainty_score":0.04838365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08579226792601731,"score_gpt":0.383519142950306,"score_spread":0.2977268750242887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}