{"id":"W3001161720","doi":"10.1016/j.cjca.2020.01.008","title":"Humanized Monoclonal Antibodies Against IgE Antibodies as Therapy for IgE-Mediated Coronary Syndromes: Are We There Yet?","year":2020,"lang":"en","type":"letter","venue":"Canadian Journal of Cardiology","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Immunoglobulin E; Degranulation; Immunology; Antibody; Antigen; Medicine; Mast cell; CD23; Omalizumab; Receptor; Allergy; Monoclonal antibody; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001289807,0.000544447,0.001425663,0.0005457118,0.001706368,0.001905757,0.001250667,0.03397685,0.004351731],"category_scores_gemma":[0.007640149,0.0004037851,0.0009692282,0.0005255009,0.001987562,0.00201327,0.0004430246,0.01501102,0.002488222],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004699587,"about_ca_system_score_gemma":0.002606145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006874936,"about_ca_topic_score_gemma":0.01336492,"domain_scores_codex":[0.9988638,0.0002846928,0.0001345806,0.0001080839,0.0003929791,0.0002159091],"domain_scores_gemma":[0.9970701,0.001577046,0.0001929001,0.00006669795,0.0004164774,0.0006767048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006686722,0.0003221835,0.004006654,0.000268523,0.00009953238,0.07728113,0.0002794992,0.0003082193,0.00108399,0.007417889,0.857259,0.05100473],"study_design_scores_gemma":[0.001232869,0.0004594356,0.006036662,0.000658614,0.0002172175,0.06019896,0.0006029516,0.00198981,0.0007319864,0.01450571,0.9132383,0.0001275297],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.003998097,0.01399872,0.0003486652,0.9459135,0.02648846,0.00003218035,0.00005795668,0.0000437,0.009118574],"genre_scores_gemma":[0.05404318,0.01390164,0.001256374,0.7760814,0.1413916,0.00008193675,0.00008809665,0.00003347,0.01312217],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03397685,"threshold_uncertainty_score":0.03409803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03053896311301149,"score_gpt":0.2390728924518217,"score_spread":0.2085339293388102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}