{"id":"W3001330686","doi":"10.1096/fj.201900547rr","title":"Persistent myopathy despite release of partial obstruction: in vivo reversal of dysfunction and transcriptional responses using rapamycin","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Glycogen Storage Diseases and Myoclonus","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Biotechnology and Biological Sciences Research Council; Natural Sciences and Engineering Research Council of Canada; Sickkids Research Institute; Canadian Institutes of Health Research; Hospital for Sick Children; University of Toronto; Deutsche Forschungsgemeinschaft","keywords":"In vivo; Myopathy; Medicine; Neuroscience; Psychology; Biology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004398698,0.0004569046,0.0005805002,0.000382136,0.0002716649,0.0003274897,0.0003166476,0.0004953638,0.001457536],"category_scores_gemma":[0.0001479771,0.0002580573,0.0005778325,0.0002286941,0.0005372625,0.0004017325,0.000250356,0.001391265,0.000401556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001635598,"about_ca_system_score_gemma":0.0003741204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004491867,"about_ca_topic_score_gemma":0.0009852978,"domain_scores_codex":[0.9996382,0.00005430948,0.0000505265,0.00008544586,0.00004800521,0.0001234832],"domain_scores_gemma":[0.9996722,0.00004065628,0.00008200867,0.00003771382,0.00001985066,0.0001475889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001504725,0.0005149281,0.0001886591,0.00009727439,0.00001340479,0.00007368661,0.00004190352,0.00008356375,0.9956697,0.00006930361,0.00009938604,0.001643452],"study_design_scores_gemma":[0.0002549311,0.0134402,0.01188633,0.00003030245,0.00007721961,0.0003750419,0.0001975927,0.001326296,0.9699765,0.00007840333,0.002337034,0.00002013812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99575,0.001230309,0.001261362,0.0001677295,0.0001202441,0.00006687111,0.0005164948,0.0001158609,0.0007711726],"genre_scores_gemma":[0.9906907,0.001622562,0.002551264,0.0001131272,0.0000647967,0.000236871,0.001015794,0.00004621828,0.003658609],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001457536,"threshold_uncertainty_score":0.004875958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03770400671881348,"score_gpt":0.2518793930439437,"score_spread":0.2141753863251303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}