{"id":"W3001412508","doi":"10.1016/j.pnpbp.2020.109873","title":"Understanding the neurobiological effects of drug abuse: Lessons from zebrafish models","year":2020,"lang":"en","type":"review","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul; University of Toronto; Natural Sciences and Engineering Research Council of Canada; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Zebrafish; Danio; Neurochemical; Addiction; Drugs of abuse; Drug; Neuroscience; Nicotine; Substance abuse; Psychology; Medicine; Bioinformatics; Biology; Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004013579,0.0006398269,0.001374465,0.0001306541,0.000184196,0.00003833377,0.001342495,0.001004948,0.00002934918],"category_scores_gemma":[0.0002220581,0.0003832708,0.0004367039,0.0006027627,0.001952655,0.000008571063,0.0005988727,0.001548048,0.00000918122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002932179,"about_ca_system_score_gemma":0.0002086823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002433177,"about_ca_topic_score_gemma":0.000007245273,"domain_scores_codex":[0.9953586,0.001371612,0.000900812,0.001476133,0.0002234014,0.0006693951],"domain_scores_gemma":[0.9974564,0.00120208,0.0004564944,0.0005263892,0.00003896616,0.0003196119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003700513,0.005783761,0.02479838,0.01505138,0.00315914,0.0004289559,0.0003133154,0.00001002406,0.001248127,0.01691998,0.06512077,0.8634657],"study_design_scores_gemma":[0.003831273,0.001575507,0.004257959,0.001661178,0.0006441971,0.00008331741,0.00006326479,0.0001161984,0.00002562449,0.02011277,0.9664379,0.001190762],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005590266,0.9875265,0.0003145089,0.003181157,0.0009757849,0.00204856,0.0002137572,0.00004713402,0.0001023714],"genre_scores_gemma":[0.03870067,0.9578433,0.000229386,0.001532264,0.0005851508,0.0007849156,0.0002666739,0.00004928332,0.000008369186],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9013172,"threshold_uncertainty_score":0.9998619,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08244931457671723,"score_gpt":0.3849443020785783,"score_spread":0.3024949875018611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}