{"id":"W3001415022","doi":"10.1016/j.jhep.2020.01.007","title":"Hepatocellular carcinoma prediction beyond year 5 of oral therapy in a large cohort of Caucasian patients with chronic hepatitis B","year":2020,"lang":"en","type":"article","venue":"Journal of Hepatology","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"Merck Sharp and Dohme; Gilead Sciences; Novartis; Janssen Biotech; MedImmune; Roche; AbbVie; Merck; Siemens; Bristol-Myers Squibb","keywords":"Medicine; Hepatocellular carcinoma; Internal medicine; Cirrhosis; Entecavir; Gastroenterology; Cumulative incidence; Incidence (geometry); Cohort; Hepatitis B; Chronic hepatitis; Immunology; Lamivudine; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008138973,0.0003445691,0.0004705949,0.0004498601,0.0006997986,0.0005406744,0.0002648528,0.0003899394,0.0008600455],"category_scores_gemma":[0.001185995,0.0003597431,0.0005053872,0.0005512714,0.0002006256,0.000400974,0.0004260082,0.0005038007,0.0002777835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000317543,"about_ca_system_score_gemma":0.0004651208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01053906,"about_ca_topic_score_gemma":0.01135386,"domain_scores_codex":[0.9996997,0.0001071799,0.00002572786,0.00007145041,0.00004604557,0.00004997513],"domain_scores_gemma":[0.9990514,0.0001094822,0.0003134573,0.00006949285,0.0001271419,0.0003289293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002352231,0.00006475593,0.9987313,0.000004988329,0.00002753332,0.00004777946,0.00005748136,0.00001489452,0.0001916833,0.000003607145,0.00005014584,0.000570634],"study_design_scores_gemma":[0.00002107294,0.0002544872,0.9991851,0.000003326724,0.00002127085,0.0001430094,0.0001143073,0.0001266343,0.00003429334,0.000004217374,0.00008959635,0.000002647575],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997049,0.00005044128,0.0000281434,0.000008716997,0.000002477097,0.00001020087,0.000108817,0.00000117179,0.00008511135],"genre_scores_gemma":[0.9993846,0.00004954266,0.00006331759,0.00001440261,0.000007931151,0.00001324797,0.0003558058,9.705118e-7,0.0001101379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01053906,"threshold_uncertainty_score":0.02095544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.021858769239791,"score_gpt":0.2257571492467275,"score_spread":0.2038983800069365,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}