{"id":"W3001417722","doi":"10.1152/ajpendo.00361.2019","title":"TGF-β1 promotes vitamin D-induced prostaglandin E2 synthesis by upregulating vitamin D receptor expression in human granulosa-lutein cells","year":2020,"lang":"en","type":"article","venue":"American Journal of Physiology-Endocrinology and Metabolism","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Calcitriol receptor; Endocrinology; Internal medicine; Receptor; Transforming growth factor; Signal transduction; Chemistry; Prostaglandin E2 receptor; Biology; Cell biology; Cancer research; Vitamin D and neurology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001982668,0.0001939254,0.0003562241,0.0003201118,0.0001800057,0.0003377179,0.00009398883,0.0002005667,0.001627486],"category_scores_gemma":[0.0001114356,0.0001397004,0.0003349932,0.000226988,0.0001923441,0.0001268334,0.0001861224,0.0004456146,0.0005281367],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000218775,"about_ca_system_score_gemma":0.0002397678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001180539,"about_ca_topic_score_gemma":0.001181697,"domain_scores_codex":[0.9998699,0.00002199843,0.00001685874,0.00002792759,0.00003197209,0.00003138265],"domain_scores_gemma":[0.999945,0.00001359176,0.00001064648,0.000008727411,0.000009028413,0.00001299909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004230943,0.00007576041,0.0007947361,0.0001414669,0.00001085862,0.0001652484,0.0001134526,0.00004161074,0.9942957,0.0001042858,0.0001487032,0.003684995],"study_design_scores_gemma":[0.0002617642,0.0007765703,0.02119974,0.00002667029,0.00006393887,0.000654912,0.000225925,0.001222733,0.9552067,0.0001236572,0.02022336,0.00001399902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9790823,0.01277828,0.003457549,0.0004282377,0.0001136414,0.0001035273,0.0008533683,0.0001239065,0.003059171],"genre_scores_gemma":[0.9897171,0.003359982,0.002327632,0.0002194238,0.00003858111,0.00008104107,0.0009008154,0.00001390866,0.003341463],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001627486,"threshold_uncertainty_score":0.005444467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008271146629736215,"score_gpt":0.2362423203319547,"score_spread":0.2279711737022185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}