{"id":"W3001580671","doi":"10.1136/bmjopen-2019-033702","title":"HEV study protocol : design of a cluster-randomised, blinded trial to assess the safety, immunogenicity and effectiveness of the hepatitis E vaccine HEV 239 (Hecolin) in women of childbearing age in rural Bangladesh","year":2020,"lang":"en","type":"article","venue":"BMJ Open","topic":"Hepatitis Viruses Studies and Epidemiology","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Health Economics","funders":"Norwegian Institute of Public Health; International Centre for Diarrhoeal Disease Research, Bangladesh; Norges Forskningsråd","keywords":"Medicine; Hepatitis E virus; Vaccination; Hepatitis A vaccine; Hepatitis E; Pregnancy; Immunogenicity; Viral hepatitis; Randomized controlled trial; Public health; Hepatitis A; Environmental health; Hepatitis; Pediatrics; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006553628,0.0001885937,0.001489174,0.00007164825,0.00006331508,0.00001239259,0.0004654461,0.00008081988,0.00002518839],"category_scores_gemma":[0.002982012,0.0001113739,0.00009463369,0.000485161,0.00006832097,0.00006980143,0.001124676,0.0002413177,6.687679e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001181808,"about_ca_system_score_gemma":0.0002011028,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01165987,"about_ca_topic_score_gemma":0.005661292,"domain_scores_codex":[0.9950407,0.002941873,0.001216187,0.0002756702,0.0002377924,0.0002877677],"domain_scores_gemma":[0.9973355,0.001697135,0.0003959618,0.0004159211,0.00008171057,0.0000737548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.3821557,0.0004773471,0.6101642,0.000369761,0.0001774186,0.00001267742,0.004516767,0.0004653838,0.0008853712,0.00001343708,0.00002965609,0.0007322744],"study_design_scores_gemma":[0.2133249,0.003537877,0.7806208,0.0006468035,0.00004235721,0.000003656367,0.0008125655,0.0003985619,0.000449878,0.00004529277,0.00002066544,0.00009666535],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7156308,0.000007636296,0.0001355006,0.0004999208,0.00003705738,0.2835917,0.000008519211,0.000003365197,0.00008552832],"genre_scores_gemma":[0.8794081,0.00001933565,0.0001267892,0.0003381644,0.00004318005,0.1200436,0.000001132922,0.00001600919,0.000003692428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1704566,"threshold_uncertainty_score":0.9949216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1395234758881083,"score_gpt":0.4251703978664539,"score_spread":0.2856469219783455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}