{"id":"W3001580671","doi":"10.1136/bmjopen-2019-033702","title":"HEV study protocol : design of a cluster-randomised, blinded trial to assess the safety, immunogenicity and effectiveness of the hepatitis E vaccine HEV 239 (Hecolin) in women of childbearing age in rural Bangladesh","year":2020,"lang":"en","type":"article","venue":"BMJ Open","topic":"Hepatitis Viruses Studies and Epidemiology","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Health Economics","funders":"Norwegian Institute of Public Health; International Centre for Diarrhoeal Disease Research, Bangladesh; Norges Forskningsråd","keywords":"Medicine; Hepatitis E virus; Vaccination; Hepatitis A vaccine; Hepatitis E; Pregnancy; Immunogenicity; Viral hepatitis; Randomized controlled trial; Public health; Hepatitis A; Environmental health; Hepatitis; Pediatrics; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02043748,0.004850118,0.008250783,0.001339499,0.001894666,0.002493755,0.002828489,0.00574325,0.04316202],"category_scores_gemma":[0.01829228,0.002282296,0.00274314,0.001474521,0.003151758,0.002261225,0.001627117,0.00434903,0.006684893],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003149533,"about_ca_system_score_gemma":0.01195258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002115663,"about_ca_topic_score_gemma":0.00331527,"domain_scores_codex":[0.9849232,0.00974879,0.001321744,0.001622627,0.0009445698,0.001439062],"domain_scores_gemma":[0.9900461,0.00265042,0.002371186,0.001315703,0.001572301,0.002044288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9763656,0.006771133,0.0005116096,0.002648158,0.0006259065,0.00003174774,0.0001111315,0.00053308,0.0005376128,0.0005932217,0.002261418,0.009009285],"study_design_scores_gemma":[0.9625257,0.0319359,0.0007941158,0.0002756045,0.0002469038,0.0000119962,0.00002870318,0.0004835375,0.0001846288,0.0005061346,0.002980554,0.00002619348],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.02209325,0.0004873146,0.001994492,0.0003352271,0.000669902,0.9703501,0.00228227,0.0001384216,0.001648909],"genre_scores_gemma":[0.01826211,0.0001923539,0.003243314,0.0003789846,0.0001573241,0.9764462,0.0003385649,0.000009884023,0.0009711849],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.04316202,"threshold_uncertainty_score":0.1443914,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1395234758881083,"score_gpt":0.4251703978664539,"score_spread":0.2856469219783455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}