{"id":"W3002184483","doi":"10.1093/molbev/msaa009","title":"Evolution of Transcriptional Repressors Impacts <i>Caenorhabditis</i> Vulval Development","year":2020,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of General Medical Sciences; Pelotonia; Natural Sciences and Engineering Research Council of Canada; California Institute of Technology; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Biology; Caenorhabditis elegans; Caenorhabditis; Genetics; Gene; Phenotype; Chromatin; Genome; Epigenetics; Conserved sequence; Ectopic expression; Histone; Peptide sequence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001481654,0.0003343424,0.0001777751,0.0003862407,0.000210505,0.0003601278,0.0003797241,0.0002773061,0.0006432833],"category_scores_gemma":[0.0001712481,0.0002080243,0.0002034095,0.0001363179,0.000292786,0.0001489671,0.0003690233,0.0004562037,0.0003003259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007014163,"about_ca_system_score_gemma":0.0002872328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001902585,"about_ca_topic_score_gemma":0.002975675,"domain_scores_codex":[0.9998587,0.00001050598,0.00001015228,0.00005079699,0.00003859293,0.00003122508],"domain_scores_gemma":[0.9998524,0.00002072118,0.00005966184,0.0000181574,0.00001540567,0.00003355652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000252918,0.000005656548,0.0006765361,0.000007932359,0.000002710076,0.00003557468,0.000007822027,0.00007324247,0.9982755,0.0001167788,0.00001138764,0.0007614988],"study_design_scores_gemma":[0.00002928065,0.0002486554,0.1114381,0.00001855579,0.00006676246,0.001409916,0.0001102808,0.004148415,0.8744834,0.0003384072,0.007677703,0.00003058819],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961352,0.0004861486,0.001746752,0.00004387718,0.000006668967,0.000007873237,0.0001529276,0.0001069828,0.001313595],"genre_scores_gemma":[0.9962147,0.000267939,0.001519075,0.00005465754,0.000003755925,0.00001021332,0.0003637113,0.00005324282,0.001512573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001902585,"threshold_uncertainty_score":0.005089104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008064132074869829,"score_gpt":0.2293903861577413,"score_spread":0.2213262540828715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}