{"id":"W3002562631","doi":"10.1139/bcb-2019-0339","title":"Exogenous ubiquitin attenuates hypoxia/reoxygenation-induced cardiac myocyte apoptosis via the involvement of CXCR4 and modulation of mitochondrial homeostasis","year":2020,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; U.S. Department of Veterans Affairs","keywords":"Mitochondrial biogenesis; Protein kinase B; Apoptosis; Mitochondrion; Cell biology; GSK-3; Oxidative stress; Myocyte; Biology; GSK3B; Mitochondrial fission; Signal transduction; Chemistry; Endocrinology; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001433311,0.0002612591,0.0002522769,0.000155162,0.0001598654,0.0001471281,0.0001508698,0.0001867418,0.001017587],"category_scores_gemma":[0.00006705374,0.00008261004,0.0002090907,0.00009917485,0.0001595224,0.000184715,0.0001331402,0.0003706254,0.0001283934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001600387,"about_ca_system_score_gemma":0.0001921709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003490807,"about_ca_topic_score_gemma":0.0006932988,"domain_scores_codex":[0.9999079,0.00001870351,0.00001011045,0.00001410746,0.00001696758,0.00003222253],"domain_scores_gemma":[0.9999596,0.000003125581,0.00001569721,0.00000493703,0.000005776042,0.00001085841],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008418475,0.00025317,0.0004574584,0.000157886,0.00002285418,0.00006477991,0.00002229053,0.0001020518,0.9906778,0.0001712155,0.0001330471,0.007095543],"study_design_scores_gemma":[0.0001407996,0.002206059,0.01292599,0.0000211852,0.00005264511,0.0002885491,0.00004442279,0.0009549818,0.9801956,0.00006315871,0.003098692,0.000007915892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925696,0.004823895,0.001251437,0.0001239123,0.00003732166,0.00003154546,0.0001506492,0.00005057186,0.0009610432],"genre_scores_gemma":[0.9950463,0.001953509,0.001094428,0.00006726754,0.00001417261,0.00004603256,0.0002586773,0.00000678799,0.001512968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001017587,"threshold_uncertainty_score":0.0034042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01625430019050235,"score_gpt":0.221782345435941,"score_spread":0.2055280452454386,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}