{"id":"W3003228485","doi":"10.1038/s41591-019-0747-1","title":"Combination anti-HIV-1 antibody therapy is associated with increased virus-specific T cell immunity","year":2020,"lang":"en","type":"article","venue":"Nature Medicine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":164,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Center for AIDS Research, University of Washington; City University of New York; Nature; Universitätsklinikum Köln; Université de Montréal; National Institutes of Health; U.S. Department of Health and Human Services; Einstein-Rockefeller-CUNY Center for AIDS Research, Albert Einstein College of Medicine; Government of Canada; Canadian Institutes of Health Research; Bill and Melinda Gates Foundation; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute","keywords":"Viremia; Immunology; Antibody; T cell; Virology; CD8; Viral load; Virus; Epitope; Immune system; Immunity; Adjuvant; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002527109,0.0002132646,0.0003908429,0.00009466778,0.0002118938,0.000008805813,0.0002267285,0.0003964011,0.00226501],"category_scores_gemma":[0.0001356355,0.0001324621,0.00004703796,0.0004206974,0.0002751522,0.00005742577,0.00003272943,0.001166995,0.0006229708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004945427,"about_ca_system_score_gemma":0.00006597565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001175525,"about_ca_topic_score_gemma":0.000007780012,"domain_scores_codex":[0.9987213,0.0003275128,0.0001887239,0.0002914867,0.0001400287,0.0003309328],"domain_scores_gemma":[0.9991621,0.0002180435,0.000107052,0.000245933,0.0001878937,0.00007892175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007666379,0.0007190998,0.02570031,0.00001305379,0.0004239085,0.00009641852,0.001447523,2.21734e-7,0.9020814,0.00008278258,0.06737473,0.001293874],"study_design_scores_gemma":[0.02880001,0.004144463,0.3269136,0.0001280226,0.00007700102,0.0000222077,0.0004131917,0.00000611407,0.4376476,0.0000362204,0.2014874,0.0003241842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9705809,0.01819831,0.00005077769,0.006888624,0.0001518224,0.0004256867,0.0001978338,0.0001081127,0.003397977],"genre_scores_gemma":[0.9909049,0.001579755,0.00001096819,0.002357055,0.00005818553,0.00001000786,0.004639333,0.00002040082,0.0004194534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4644338,"threshold_uncertainty_score":0.998647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01475603272088247,"score_gpt":0.2738710867528425,"score_spread":0.25911505403196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}