{"id":"W3003414630","doi":"10.25251/skin.4.supp.46","title":"Long-Term Safety of Certolizumab Pegol in Plaque Psoriasis: Pooled Analysis over 3 Years from Three Phase 3, Randomized, Placebo-Controlled Studies","year":2020,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"UCB Pharma; National Institute for Health and Care Research; Manchester Biomedical Research Centre; Dermira","keywords":"Certolizumab pegol; Medicine; Placebo; Term (time); Randomized controlled trial; Psoriasis; Plaque psoriasis; Internal medicine; Dermatology; Adalimumab; Alternative medicine; Pathology; Disease; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007780848,0.0003276286,0.003134331,0.0003707256,0.00007923176,0.000005062611,0.000457323,0.0001928373,0.00107039],"category_scores_gemma":[0.001169797,0.0001765444,0.0006827635,0.0005062169,0.000469249,0.00006106638,0.00006240384,0.000403141,0.00001814615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008345892,"about_ca_system_score_gemma":0.00009727266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001602406,"about_ca_topic_score_gemma":0.0005223415,"domain_scores_codex":[0.9963225,0.001332136,0.00162405,0.0002153544,0.0002111361,0.0002948751],"domain_scores_gemma":[0.9941315,0.003997169,0.001325148,0.0002955922,0.0001847078,0.00006590557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9047949,0.000348394,0.00279513,0.00003101001,0.05180534,0.002534863,0.01183383,0.0002444038,0.0113388,0.0000248033,0.0006517167,0.01359677],"study_design_scores_gemma":[0.9340429,0.001733085,0.003984911,0.0004385145,0.05146915,0.002142634,0.002176467,0.0001658545,0.003010383,0.0004146989,0.0001208417,0.0003005538],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9449167,0.04990585,0.0004578817,0.003082235,0.0007618756,0.000709052,0.00005742344,0.00001297512,0.00009604614],"genre_scores_gemma":[0.9920671,0.007255351,0.00003116397,0.0001418675,0.0003309917,0.00001126587,0.00003747087,0.00001983563,0.0001049773],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04715042,"threshold_uncertainty_score":0.9998428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01792305737912041,"score_gpt":0.2818533064182505,"score_spread":0.26393024903913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}