{"id":"W3003420651","doi":"10.1093/ndt/gfz230","title":"Renal physiology of glucose handling and therapeutic implications","year":2019,"lang":"en","type":"review","venue":"Nephrology Dialysis Transplantation","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; Toronto General Hospital; Diabetes Canada; University of Toronto","funders":"Canadian Institutes of Health Research; Department of Medicine, University of Toronto; University of Toronto; Diabetes Canada; Heart and Stroke Foundation of Canada","keywords":"Medicine; Empagliflozin; Glycemic; Renal function; Type 2 diabetes; Diabetes mellitus; Canagliflozin; Kidney disease; Albuminuria; Internal medicine; Clinical trial; Dapagliflozin; Intensive care medicine; Endocrinology; Urology; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002002612,0.0005369664,0.001212967,0.0006162417,0.0004752514,0.003419529,0.001083557,0.001983727,0.003076225],"category_scores_gemma":[0.002609204,0.0002139361,0.0007255158,0.0005685234,0.002654212,0.00180452,0.00160204,0.004805699,0.0008016336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001202622,"about_ca_system_score_gemma":0.001627698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009057887,"about_ca_topic_score_gemma":0.0005291505,"domain_scores_codex":[0.9987702,0.0005152283,0.0001095663,0.0001940379,0.0002792957,0.0001317032],"domain_scores_gemma":[0.9989065,0.0003739455,0.0001330097,0.0001416335,0.0002539312,0.0001910373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001731619,0.0006898551,0.008825708,0.003046383,0.0003176626,0.003014572,0.0006937602,0.001797226,0.01863202,0.2551868,0.03784395,0.6682204],"study_design_scores_gemma":[0.0004173347,0.00189848,0.0274248,0.002966955,0.0003081803,0.01425134,0.001010379,0.002705907,0.008095497,0.2799119,0.6607863,0.0002227414],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03182843,0.7096449,0.01991765,0.1604652,0.005803821,0.00008936143,0.0002689541,0.0002855214,0.07169622],"genre_scores_gemma":[0.4672045,0.4316849,0.01404599,0.05398462,0.02149994,0.0003281086,0.000286974,0.0001715647,0.01079345],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003419529,"threshold_uncertainty_score":0.01059097,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03682037251775153,"score_gpt":0.3148890625277778,"score_spread":0.2780686900100262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}