{"id":"W3003747453","doi":"10.1016/j.jtho.2020.01.016","title":"New Approaches to SCLC Therapy: From the Laboratory to the Clinic","year":2020,"lang":"en","type":"review","venue":"Journal of Thoracic Oncology","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":176,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Janssen Pharmaceuticals; National Cancer Institute; National Health and Medical Research Council; Daiichi Sankyo Europe; Agios Pharmaceuticals; Karolinska Institutet; Takeda Oncology; EMD Serono; Ipsen; PharmaMar; Astellas Pharma; Merck; Kyowa Hakko Kirin; Daiichi-Sankyo; Syndax Pharmaceuticals; Cancer Research UK; AstraZeneca; International Association for the Study of Lung Cancer; Genentech; ANGLE; Bayer Fund; Meso Scale Diagnostics; Astex Pharmaceuticals; TG Therapeutics; Aeglea BioTherapeutics; Pfizer Pharmaceuticals; Marshfield Clinic Research Foundation; Memorial Sloan-Kettering Cancer Center; Merck KGaA; National Institutes of Health; Regeneron Pharmaceuticals; Victorian Cancer Agency; Incyte; Medical Research Council; University of Texas Southwestern Medical Center; AbbVie; Celgene; Novartis; Foundation Medicine; GlaxoSmithKline; Eli Lilly and Company; Bristol-Myers Squibb; G1 Therapeutics; Lung Cancer Research Foundation; Cold Spring Harbor Laboratory; Roche; Astellas Pharma US; Amgen; Ariad Pharmaceuticals; Boehringer Ingelheim; Pfizer","keywords":"Medicine; Intensive care medicine; Lung cancer; Clinical trial; Immunotherapy; Disease; Oncology; Cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002205017,0.001061779,0.003138635,0.003390466,0.0003879315,0.002386014,0.001598716,0.001877366,0.005093846],"category_scores_gemma":[0.00312878,0.0003712813,0.001044767,0.003555676,0.001247047,0.002685208,0.001211728,0.003327878,0.001347559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001665438,"about_ca_system_score_gemma":0.002936645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002296377,"about_ca_topic_score_gemma":0.005474306,"domain_scores_codex":[0.999358,0.0001835845,0.00008979902,0.0001096778,0.0002080252,0.00005094882],"domain_scores_gemma":[0.9978327,0.001520828,0.0001793731,0.00004492011,0.0003101111,0.0001120622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001821584,0.00008882155,0.0003051272,0.0413265,0.0002721597,0.0001404116,0.00006672302,0.0004009131,0.0006080385,0.00601835,0.03174546,0.9188454],"study_design_scores_gemma":[0.0001145949,0.000249021,0.001547019,0.03400218,0.0006377148,0.0008673036,0.0002101995,0.0001603894,0.0002538453,0.005331135,0.9565769,0.00004991456],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001717763,0.9994581,0.00002523127,0.0002552695,0.0001043966,0.000001279177,0.000004887569,0.000001927375,0.0001316044],"genre_scores_gemma":[0.0002264957,0.9991894,0.0000664924,0.0002776627,0.0001636307,0.00000250302,0.000007872824,5.525229e-7,0.0000652965],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005093846,"threshold_uncertainty_score":0.01704061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3638905641609863,"score_gpt":0.5524615542292449,"score_spread":0.1885709900682587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}