{"id":"W3003765619","doi":"10.1002/jmd2.12095","title":"Pre‐school neurocognitive and functional outcomes after liver transplant in children with early onset urea cycle disorders, maple syrup urine disease, and propionic acidemia: An inception cohort matched‐comparison study","year":2020,"lang":"en","type":"article","venue":"JIMD Reports","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Glenrose Rehabilitation Hospital; University of Saskatchewan; University of Alberta","funders":"Alberta Health; Women and Children's Health Research Institute; Children's Health Research Institute","keywords":"Maple syrup urine disease; Propionic acidemia; Medicine; Internal medicine; Gastroenterology; Neurocognitive; Urea cycle; Liver transplantation; Cohort; Pediatrics; Liver disease; Transplantation; Arginine; Psychiatry; Cognition; Chemistry; Biochemistry; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007396019,0.0006790888,0.0006386276,0.001468281,0.0007868426,0.0006569433,0.0005186094,0.0006165894,0.002279972],"category_scores_gemma":[0.001462955,0.0003917881,0.0007909909,0.0009351456,0.0004731939,0.0006751772,0.0006963116,0.00065197,0.0002964457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006203369,"about_ca_system_score_gemma":0.000391273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005390132,"about_ca_topic_score_gemma":0.004256189,"domain_scores_codex":[0.9995523,0.00009400531,0.00004744733,0.0001268205,0.00006297414,0.000116403],"domain_scores_gemma":[0.9990597,0.0001657054,0.000277137,0.00007586417,0.00009331603,0.0003281549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002587428,0.0007529714,0.9941325,0.00001366826,0.0001813234,0.0003927196,0.0001646873,0.0000415029,0.0004598505,0.00002586946,0.00007721148,0.001170228],"study_design_scores_gemma":[0.0003048523,0.002621412,0.9949326,0.000008175537,0.0001337924,0.0008251922,0.0005197476,0.0002299943,0.00024195,0.00002800091,0.0001425636,0.00001180835],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997887,0.00003689546,0.00001231535,0.000003804859,0.000002353045,0.000007008587,0.00007871437,5.520367e-7,0.00006964614],"genre_scores_gemma":[0.999598,0.00003194577,0.00002185108,0.000009382156,0.000006583637,0.00001262353,0.0002273158,9.064237e-7,0.00009151627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005390132,"threshold_uncertainty_score":0.01071751,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005306783882963893,"score_gpt":0.220459411748546,"score_spread":0.2151526278655821,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}