{"id":"W3003788831","doi":"10.1016/j.neuron.2020.01.003","title":"LRRTMs Organize Synapses through Differential Engagement of Neurexin and PTPσ","year":2020,"lang":"en","type":"article","venue":"Neuron","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba; University of British Columbia; Health Sciences Centre","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Manitoba; Research Manitoba","keywords":"Differential (mechanical device); Neuroscience; Neurexin; Psychology; Communication; Cognitive science; Chemistry; Postsynaptic potential; Biochemistry; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002523412,0.0002843002,0.0003710565,0.0003337315,0.0004248354,0.001392742,0.0005132456,0.0006567946,0.001630403],"category_scores_gemma":[0.0003994008,0.0003088562,0.000365514,0.0001882917,0.0003562042,0.0009346597,0.001131206,0.000828287,0.001327998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000937303,"about_ca_system_score_gemma":0.0002626897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004890262,"about_ca_topic_score_gemma":0.001381146,"domain_scores_codex":[0.9996406,0.00003285758,0.0000268677,0.00007756408,0.0001077314,0.0001144963],"domain_scores_gemma":[0.9998145,0.00002013569,0.00005844409,0.00002419716,0.00003156929,0.00005128097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007130931,0.00000484344,0.0004199607,0.00002375027,0.000006269767,0.00007726481,0.00003405052,0.00009647211,0.9972528,0.0006678081,0.00003724102,0.001308215],"study_design_scores_gemma":[0.00002073643,0.00006719822,0.0155465,0.00001901115,0.00001994633,0.0005244617,0.0002468411,0.003274044,0.9769157,0.0004497541,0.002904208,0.00001156817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892602,0.001163514,0.006401889,0.0001470364,0.00003135237,0.00001280172,0.0001052349,0.0001057313,0.002772225],"genre_scores_gemma":[0.9939643,0.0004237232,0.002513387,0.00006711875,0.00001072411,0.00001355776,0.0001273207,0.00004391683,0.002835991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001630403,"threshold_uncertainty_score":0.006800592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.018265041399947,"score_gpt":0.2200994549545754,"score_spread":0.2018344135546284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}