{"id":"W3003876562","doi":"10.1056/nejmoa1910640","title":"Fatal Cytomegalovirus Infection in an Adult with Inherited NOS2 Deficiency","year":2020,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"National Center for Advancing Translational Sciences; National Center for Research Resources; St. Giles Foundation; Qatar National Research Fund; Agence Nationale de la Recherche; American Philosophical Society","keywords":"Cytomegalovirus; Pathogenesis; Medicine; Disease; Immunology; Betaherpesvirinae; Human cytomegalovirus; Gene; Herpesviridae; Virology; Viral disease; Virus; Biology; Genetics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003364813,0.000152613,0.0003702489,0.0001912634,0.00007206868,0.000008057624,0.0001810608,0.0001036865,0.0002253398],"category_scores_gemma":[0.0002632704,0.00009866771,0.00003882343,0.0004128737,0.0001813378,0.0002427464,0.00001666476,0.0005978869,0.00002279938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002211279,"about_ca_system_score_gemma":0.0001247317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006446223,"about_ca_topic_score_gemma":0.0001080948,"domain_scores_codex":[0.9988838,0.0001616307,0.0004890693,0.0001441599,0.00008804874,0.0002333349],"domain_scores_gemma":[0.9993924,0.00006437211,0.0002597666,0.0001048956,0.0001465196,0.00003198192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.007492946,0.0005446117,0.08684366,0.00006966304,0.0001353323,0.0002965214,0.0248433,0.0008344095,0.5597002,0.0005824885,0.0008345672,0.3178223],"study_design_scores_gemma":[0.2875759,0.03483984,0.5078501,0.001213303,0.0003766461,0.005175595,0.006735027,0.0001787505,0.02302091,0.0004440701,0.1315158,0.001074003],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884627,0.006854581,0.001003986,0.002573914,0.0004379543,0.0000859849,0.000001672387,0.00002022943,0.0005589356],"genre_scores_gemma":[0.9986992,0.0002982694,0.0000351761,0.000803474,0.00009243662,8.023898e-7,0.00001875007,0.00001136866,0.00004053139],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5366793,"threshold_uncertainty_score":0.4023552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01531167660171186,"score_gpt":0.2439473254053304,"score_spread":0.2286356488036185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}