{"id":"W3003947506","doi":"10.1128/msphere.00802-19","title":"Saccharomyces cerevisiae: First Steps to a Suitable Model System To Study the Function and Intracellular Transport of Human Kidney Anion Exchanger 1","year":2020,"lang":"en","type":"article","venue":"mSphere","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Deutscher Akademischer Austausch Dienst Kairo; Deutsche Forschungsgemeinschaft","keywords":"Saccharomyces cerevisiae; Biology; Mutant; Yeast; Intracellular; Kidney; Biochemistry; Secretion; Cell biology; Computational biology; Chemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006872021,0.0008849937,0.0007769335,0.0003557532,0.0004081114,0.000918054,0.0007345323,0.0005524873,0.001178379],"category_scores_gemma":[0.0003535928,0.000338676,0.0005211701,0.0004166533,0.0002218357,0.0006516551,0.0008627849,0.001565205,0.001490578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005530764,"about_ca_system_score_gemma":0.0004034812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001526624,"about_ca_topic_score_gemma":0.002446678,"domain_scores_codex":[0.9996907,0.0001145872,0.00005245329,0.00004767581,0.00007123646,0.00002341207],"domain_scores_gemma":[0.9998109,0.00004680163,0.0000214268,0.00004565382,0.00003118963,0.00004405769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000148678,0.0001052494,0.0004618756,0.0003486171,0.00002604839,0.0002973015,0.00009579265,0.0003133219,0.987822,0.00255743,0.0009646505,0.006858919],"study_design_scores_gemma":[0.00008485442,0.0007675311,0.002856148,0.0001175069,0.0001025482,0.001363137,0.0002522442,0.007111529,0.8507029,0.002009961,0.1345711,0.00006057255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6624722,0.0410028,0.2487731,0.00743014,0.002035876,0.00154364,0.01901002,0.002880642,0.0148516],"genre_scores_gemma":[0.6386533,0.02910574,0.2930193,0.0004786616,0.000148728,0.0006886071,0.02616641,0.0009597067,0.01077947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001526624,"threshold_uncertainty_score":0.004012823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01683006773803301,"score_gpt":0.2242520720193232,"score_spread":0.2074220042812902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}