{"id":"W3003963156","doi":"10.1002/glia.23787","title":"Epigenomic and transcriptional determinants of microglial cell identity","year":2020,"lang":"en","type":"article","venue":"Glia","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Scottish Rite Charitable Foundation of Canada; Brain and Behavior Research Foundation","keywords":"Biology; Epigenomics; Identity (music); Epigenesis; Neuroscience; Computational biology; DNA methylation; Cell biology; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002880805,0.0001966355,0.0002606306,0.0005320538,0.0001671248,0.0006530337,0.0001888234,0.0003444855,0.001707473],"category_scores_gemma":[0.000468214,0.0001501791,0.0001912554,0.0003027808,0.0004531695,0.0005117081,0.0003944164,0.0004084911,0.000403246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002745554,"about_ca_system_score_gemma":0.0002218942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004672906,"about_ca_topic_score_gemma":0.0009687864,"domain_scores_codex":[0.9998029,0.00003630599,0.00001269501,0.00007328587,0.00004168477,0.00003306262],"domain_scores_gemma":[0.9997281,0.00008158974,0.00008971286,0.00002427463,0.00005202918,0.00002416519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000305393,0.00001630337,0.009987508,0.0005601618,0.00007095004,0.0008948596,0.0006033037,0.0005000905,0.8960856,0.01453918,0.0006910064,0.07574552],"study_design_scores_gemma":[0.00002023476,0.0004014555,0.3052366,0.0004342462,0.0003497936,0.005496656,0.001336135,0.002265041,0.4565727,0.01662635,0.21115,0.0001108676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6563141,0.2180953,0.08345068,0.001720355,0.0003541749,0.00008228544,0.005343744,0.0003312712,0.03430809],"genre_scores_gemma":[0.916056,0.06091902,0.01128922,0.000356996,0.0002110811,0.0000787676,0.002103602,0.00007236681,0.008912951],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001707473,"threshold_uncertainty_score":0.005712032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04936868874984351,"score_gpt":0.2558057913213785,"score_spread":0.206437102571535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}