{"id":"W3003963156","doi":"10.1002/glia.23787","title":"Epigenomic and transcriptional determinants of microglial cell identity","year":2020,"lang":"en","type":"article","venue":"Glia","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Scottish Rite Charitable Foundation of Canada; Brain and Behavior Research Foundation","keywords":"Biology; Epigenomics; Identity (music); Epigenesis; Neuroscience; Computational biology; DNA methylation; Cell biology; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004114027,0.00006936715,0.0000944584,0.00002680972,0.00006388632,0.00002740484,0.0001092594,0.00002328972,0.0001267522],"category_scores_gemma":[0.00005247657,0.00007229484,0.00003388382,0.00007503892,0.00003937057,0.0001933256,0.00002621404,0.00005549654,0.00007304488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003161932,"about_ca_system_score_gemma":0.0000184885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002113775,"about_ca_topic_score_gemma":0.000005207347,"domain_scores_codex":[0.9993072,0.00005499724,0.0001859102,0.0002199985,0.0001410106,0.00009088048],"domain_scores_gemma":[0.9997506,0.00001961693,0.00006689644,0.00007082761,0.00001380541,0.00007829353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002049829,0.00001254149,0.0001277173,0.00001850209,2.18893e-7,0.000008392612,0.0002786004,0.000005773009,0.9967,0.002544504,0.00005470341,0.0002285472],"study_design_scores_gemma":[0.0003255836,0.00005893857,0.0009161582,0.000001532601,0.000004064262,0.000008867418,0.000006854529,0.0009139196,0.996822,0.0002655346,0.0006139858,0.00006254687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998267,0.00002004574,0.0009269505,0.0002434247,0.0001916735,0.0001062411,0.00005524153,0.00003082055,0.0001585971],"genre_scores_gemma":[0.9982563,0.00004079422,0.0002164906,0.001236209,0.00005222229,0.000001929091,8.915628e-7,0.000007970427,0.0001871488],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002278969,"threshold_uncertainty_score":0.2948098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04936868874984351,"score_gpt":0.2558057913213785,"score_spread":0.206437102571535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}