{"id":"W3004062221","doi":"10.4049/jimmunol.1900744","title":"Epigenetic Heterogeneity and Mitotic Heritability Prime Endothelial Cell Gene Induction","year":2020,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto; Toronto General Hospital; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Epigenetics; Biology; DNA methylation; Gene expression; Gene; Transcription factor; Gene expression profiling; Population; Regulation of gene expression; Genetics; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008755299,0.00006861352,0.000111101,0.0001458018,0.0001089991,0.0002512915,0.00008731463,0.0001083593,0.000760229],"category_scores_gemma":[0.0001921366,0.00009855942,0.00007989898,0.000098516,0.0001273679,0.0001102497,0.0001912828,0.0002518009,0.0001215275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002015283,"about_ca_system_score_gemma":0.00007156641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003055499,"about_ca_topic_score_gemma":0.0005823502,"domain_scores_codex":[0.99992,0.00001093252,0.000004520178,0.00002689446,0.00001906545,0.00001859455],"domain_scores_gemma":[0.9998474,0.00003291937,0.00005236035,0.00002177797,0.00002401522,0.00002153497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005531899,0.000005216666,0.001368892,0.00001129603,0.000002937788,0.00003875649,0.0000176033,0.0000550783,0.9969059,0.0001739807,0.0000203446,0.001344685],"study_design_scores_gemma":[0.00001328019,0.00024154,0.1436764,0.000009998253,0.00001996331,0.0004716661,0.0001312086,0.001659721,0.8503527,0.0005039481,0.00291074,0.000008850388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955858,0.0007715416,0.002485795,0.00004239766,0.000009802183,0.000006122985,0.0001252054,0.00002324507,0.0009499314],"genre_scores_gemma":[0.9990221,0.0001362544,0.0002534519,0.00001213554,0.000005554434,0.000004691231,0.00007978825,0.000003535577,0.0004824669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000760229,"threshold_uncertainty_score":0.002543211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01536407389414511,"score_gpt":0.2367762958038143,"score_spread":0.2214122219096692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}