{"id":"W3004119924","doi":"10.1016/j.jbiotec.2020.01.015","title":"Serum-free production of rVSV-ZEBOV in Vero cells: Microcarrier bioreactor versus scale-X™ hydro fixed-bed","year":2020,"lang":"en","type":"article","venue":"Journal of Biotechnology","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Vero cell; Microcarrier; Ebola vaccine; Virology; Bioprocess; Ebola virus; Vesicular stomatitis virus; Ebolavirus; Biology; Microbiology; Virus; Cell culture","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000267014,0.0003121378,0.0004495132,0.0001802449,0.0001271595,0.0004350568,0.0003596485,0.000301895,0.0005161914],"category_scores_gemma":[0.0001598817,0.0001145611,0.0003724401,0.0002435078,0.0001460255,0.0003353265,0.0002123323,0.0004837467,0.000314638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002683592,"about_ca_system_score_gemma":0.0001773759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00124761,"about_ca_topic_score_gemma":0.001436703,"domain_scores_codex":[0.9998479,0.00002179531,0.00001835475,0.0000331352,0.00004844483,0.00003037568],"domain_scores_gemma":[0.9999264,0.00002232998,0.00001754874,0.00001172408,0.00001116235,0.00001076177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004946114,0.00001317547,0.00006197514,0.00001929091,0.000002348304,0.00001221894,0.000007710749,0.00004726421,0.9993876,0.00002128217,0.00000692652,0.0003706698],"study_design_scores_gemma":[0.000004966804,0.00009735968,0.0004920596,0.000001721945,0.000007518119,0.00002148777,0.000006878175,0.0004448062,0.9986166,0.00001075546,0.0002936046,0.00000212974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908363,0.0007534164,0.006898945,0.00006150815,0.00004229442,0.00004026017,0.000495437,0.0000983461,0.0007735999],"genre_scores_gemma":[0.9860612,0.0005561093,0.008840284,0.00002904853,0.00001405426,0.00002848611,0.001370713,0.00003806044,0.003062052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00124761,"threshold_uncertainty_score":0.002480626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02655431831928598,"score_gpt":0.2906357258636917,"score_spread":0.2640814075444058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}