{"id":"W3004177698","doi":"10.1093/infdis/jiaa030","title":"Neonatal BCG Vaccination Reduces Interferon-γ Responsiveness to Heterologous Pathogens in Infants From a Randomized Controlled Trial","year":2020,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Immune responses and vaccinations","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Health and Medical Research Council; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; University of Melbourne; Clifford Craig Foundation","keywords":"Heterologous; Vaccination; Immunology; Cytokine; Interferon gamma; Stimulation; Medicine; Interferon; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001024053,0.0001887507,0.001133096,0.0002817702,0.0001492912,0.00003296806,0.0002981242,0.0001101791,0.0004368797],"category_scores_gemma":[0.005689848,0.0001142482,0.0004319192,0.000239342,0.0000541331,0.0001474008,0.00009030759,0.0003251611,0.00004773697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007134587,"about_ca_system_score_gemma":0.0001935038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006757931,"about_ca_topic_score_gemma":0.00002994565,"domain_scores_codex":[0.9954762,0.003173424,0.0009203189,0.0001374944,0.00007721381,0.000215375],"domain_scores_gemma":[0.9953196,0.003636807,0.0005962375,0.0001479435,0.0002413591,0.00005807614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9730835,0.0002063917,0.0002857273,0.00000333207,0.0005788771,0.0000200344,0.00211548,0.0003492009,0.01910551,0.00001724579,0.0003199021,0.00391478],"study_design_scores_gemma":[0.9833285,0.002205743,0.008303085,0.00005732423,0.0005939602,0.00009510254,0.0005563893,0.00004521656,0.004095946,0.0002694641,0.0002893543,0.0001599126],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889785,0.005719215,0.0005294179,0.002008077,0.00113624,0.001510487,0.00005057045,0.0000261248,0.00004137128],"genre_scores_gemma":[0.998813,0.0003246593,0.000005701567,0.0005513604,0.0001599893,0.0000756224,0.00001494393,0.00001438967,0.00004028307],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01500957,"threshold_uncertainty_score":0.681169,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009356270856124076,"score_gpt":0.2589495271494958,"score_spread":0.2495932562933717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}