{"id":"W3004177698","doi":"10.1093/infdis/jiaa030","title":"Neonatal BCG Vaccination Reduces Interferon-γ Responsiveness to Heterologous Pathogens in Infants From a Randomized Controlled Trial","year":2020,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Immune responses and vaccinations","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Health and Medical Research Council; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; University of Melbourne; Clifford Craig Foundation","keywords":"Heterologous; Vaccination; Immunology; Cytokine; Interferon gamma; Stimulation; Medicine; Interferon; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004508904,0.001089001,0.003598297,0.0003138013,0.0003500459,0.001020465,0.0008227928,0.001389814,0.004347614],"category_scores_gemma":[0.007160402,0.0004733426,0.002144594,0.0004150747,0.0005211488,0.0006503791,0.0004942319,0.00144794,0.0003247221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006245013,"about_ca_system_score_gemma":0.001291344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000822221,"about_ca_topic_score_gemma":0.001189846,"domain_scores_codex":[0.9969825,0.001996733,0.0003412194,0.0002733555,0.0001534274,0.0002527262],"domain_scores_gemma":[0.9974497,0.0008538504,0.0008223898,0.0001935933,0.0001627833,0.0005177353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9672149,0.001537095,0.003881391,0.00282125,0.005031002,0.00008968097,0.00006573539,0.0001671363,0.001016124,0.00005787556,0.000741659,0.01737595],"study_design_scores_gemma":[0.8839604,0.08379412,0.02029352,0.0007432349,0.008319217,0.0001218111,0.00006104752,0.000655211,0.0006369283,0.0001663354,0.001217853,0.00003031051],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9680579,0.02586909,0.0006550309,0.0009607131,0.001007646,0.001666997,0.0006102134,0.0001049943,0.001067352],"genre_scores_gemma":[0.9897783,0.005264662,0.0007765702,0.0007523142,0.0003519975,0.001983435,0.0004056958,0.00001393666,0.0006729817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004508904,"threshold_uncertainty_score":0.02384561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009356270856124076,"score_gpt":0.2589495271494958,"score_spread":0.2495932562933717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}