{"id":"W3004253465","doi":"10.3390/app10030919","title":"White Matter Network Alterations in Alzheimer’s Disease Patients","year":2020,"lang":"en","type":"article","venue":"Applied Sciences","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Janssen Alzheimer Immunotherapy Research And Development; Johnson and Johnson Pharmaceutical Research and Development; National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; H. Lundbeck A/S; Genentech; IXICO; Bristol-Myers Squibb; Gyeonggi-do Regional Research Center; Servier; Eisai; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; F. Hoffmann-La Roche; University of Southern California; Eli Lilly and Company; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Gachon University; Novartis Pharmaceuticals Corporation; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"White matter; Fractional anisotropy; Grey matter; Neuroscience; Cognitive impairment; Diffusion MRI; Alzheimer's disease; Psychology; Disease; Medicine; Audiology; Internal medicine; Cognition; Magnetic resonance imaging","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001310511,0.0001060012,0.000103933,0.00004372302,0.0004244282,0.00009183159,0.000262844,0.0000151039,0.0001470436],"category_scores_gemma":[0.0004561708,0.00009239649,0.0000258408,0.0008357188,0.0002950853,0.0002148756,0.0001416176,0.00008753408,0.0004987598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001197495,"about_ca_system_score_gemma":0.00004206993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003464671,"about_ca_topic_score_gemma":0.00001295821,"domain_scores_codex":[0.998621,0.00004761391,0.000150576,0.000550552,0.0003512478,0.0002789809],"domain_scores_gemma":[0.9990045,0.0007194591,0.00004765646,0.0001016882,0.00001315038,0.0001135854],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00006922598,0.0001046484,0.9072987,0.000005552225,0.000004004446,0.000004609421,0.0008804252,0.01614477,0.0005829447,0.01709715,0.05734607,0.0004619091],"study_design_scores_gemma":[0.0005828132,0.0001109246,0.9763994,0.00001367456,0.00001803683,4.110841e-7,0.0001571268,0.005560076,0.001255059,0.007844757,0.007618198,0.0004395595],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8466932,0.00009792517,0.0003502828,0.07855978,0.0006650171,0.0008791818,0.00003119928,0.0001504458,0.07257297],"genre_scores_gemma":[0.9600628,0.000002048905,0.0001989388,0.03951021,0.0001264678,0.00006629127,0.000001434695,0.000005790565,0.00002601841],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1133696,"threshold_uncertainty_score":0.6410714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05959961325706789,"score_gpt":0.2660454188819891,"score_spread":0.2064458056249212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}