{"id":"W3004253465","doi":"10.3390/app10030919","title":"White Matter Network Alterations in Alzheimer’s Disease Patients","year":2020,"lang":"en","type":"article","venue":"Applied Sciences","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Janssen Alzheimer Immunotherapy Research And Development; Johnson and Johnson Pharmaceutical Research and Development; National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; H. Lundbeck A/S; Genentech; IXICO; Bristol-Myers Squibb; Gyeonggi-do Regional Research Center; Servier; Eisai; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; F. Hoffmann-La Roche; University of Southern California; Eli Lilly and Company; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Gachon University; Novartis Pharmaceuticals Corporation; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"White matter; Fractional anisotropy; Grey matter; Neuroscience; Cognitive impairment; Diffusion MRI; Alzheimer's disease; Psychology; Disease; Medicine; Audiology; Internal medicine; Cognition; Magnetic resonance imaging","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001954372,0.0003125079,0.0002434883,0.001131235,0.0002573318,0.0003017238,0.0001220465,0.0002174679,0.001038427],"category_scores_gemma":[0.0009444162,0.0001432504,0.0001533222,0.0005426565,0.0001995578,0.0003452461,0.0002346966,0.0001132791,0.0001022663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002280209,"about_ca_system_score_gemma":0.0001182956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002731829,"about_ca_topic_score_gemma":0.00415505,"domain_scores_codex":[0.9999059,0.00001968561,0.00001213312,0.0000356106,0.00001519048,0.00001144736],"domain_scores_gemma":[0.9997649,0.00004061858,0.0001233304,0.00001771704,0.00002219218,0.00003129047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009227488,0.00009123689,0.9706786,0.00006409254,0.0002504108,0.001508128,0.0007652213,0.0006609595,0.01242533,0.0002382424,0.0002538635,0.01214125],"study_design_scores_gemma":[0.00000749018,0.0000846773,0.9973374,0.000004203982,0.00004560794,0.0009948455,0.0001377411,0.0006246754,0.0003803058,0.0002453282,0.0001338451,0.000003844822],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993368,0.0001158338,0.0001321344,0.00001352171,0.000001515792,0.000004809247,0.000102986,0.000004477353,0.0002878395],"genre_scores_gemma":[0.9995649,0.00006749347,0.0001056415,0.000005864065,0.000002600536,0.000004799649,0.0001602052,0.000001380434,0.00008694296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002731829,"threshold_uncertainty_score":0.005431771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05959961325706789,"score_gpt":0.2660454188819891,"score_spread":0.2064458056249212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}